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MAK057

Sigma-Aldrich

Citrate Assay Kit

sufficient for 100 colorimetric or fluorometric tests

Sinônimo(s):

Citrate Test Kit

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About This Item

Código UNSPSC:
12161503
NACRES:
NA.84

uso

sufficient for 100 colorimetric or fluorometric tests

aplicação(ões)

cosmetics
food and beverages

método de detecção

colorimetric
fluorometric

doença(s) relevante(s)

cancer

temperatura de armazenamento

−20°C

Descrição geral

Citrate is a key Tricarboxylic Acid (TCA) cycle intermediate formed by the addition of oxaloacetate to the acetyl group of acetyl-CoA. Citrate is transported out of the mitochondria via the citrate-malate shuttle and converted back to acetyl-CoA for fatty acid synthesis. Citrate is an allosteric modulator of both fatty acid synthesis via its actions on acetyl-CoA carboxylase and of glycolysis via its actions on phospho- fructokinase. Citrate metabolism and disposition can vary widely due to sex, age, and a variety of other factors including disease states. Cellular citrate levels are decreased in prostrate cancer cells and citrate levels may be a marker of prostrate cancer growth rate. The Citrate Assay Kit provides a simple, sensitive, and rapid means of quantifying citrate in a variety of samples.

Aplicação

Citrate Assay kit has been used to determine the concentration of citrate in samples.

Adequação

Suitable for the measurement of citrate in a variety of samples including tissue and cells

Princípio

Citrate concentration is determined by a coupled enzyme assay, which results in a colorimetric (570 nm)/ fluorometric (λex = 535/λem = 587 nm) product, proportional to the citrate present. Typical sensitivites of the Citrate Assay Kit are between 0.1 to 10 nmoles (2 μM-10 mM) of citrate in a variety of samples.

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Preços

Frases de perigo

H412

Declarações de precaução

P273 - P501

Classificações de perigo

Aquatic Chronic 3

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

188.6 °F - closed cup

Ponto de fulgor (°C)

87 °C - closed cup

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Certificados de análise (COA)

Lot/Batch Number
7F22K06550
6L09K06550
6D27K06550
5M05K06550
5H21K06550

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