Pular para o conteúdo
Merck
Todas as fotos(3)

Documentos

MAK053

Sigma-Aldrich

Alcohol Dehydrogenase Activity Assay Kit

sufficient for 100 colorimetric tests

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(3)

About This Item

Código UNSPSC:
12161503
NACRES:
NA.84

uso

sufficient for 100 colorimetric tests

método de detecção

colorimetric

doença(s) relevante(s)

gastrointestinal diseases

temperatura de armazenamento

−20°C

Informações sobre genes

human ... ADH1A(124) , ADH1B(125) , ADH1C(126) , ADH4(127) , ADH5(128) , ADH6(130) , ADH7(131)
mouse ... ADH1C(11522) , ADH4(26876) , ADH5(11532) , ADH6A(69117) , ADH7(11529)
rat ... ADH1C(24172) , ADH4(29646) , ADH5(100145871) , ADH6(310903) , ADH6A(295498) , ADH7(171178)

Categorias relacionadas

Descrição geral

The new Alcohol Dehydrogenase (ADH) Assay Kit, MAK498, is now available! Alcohol dehydrogenases (ADH) are a family of enzymes that catalyzes the conversion of alcohols to aldehydes, with the concomitant reduction of NAD+ to NADH. In humans, there are nine isozymes of ADH, with the majority of ADH activity occurring in the liver. ADH family members are the primary enzymes involved in alcohol detoxification. Genetic variations in ADH enzymes result in differences in ADH activity and tolerances for alcohol, and may regulate susceptibility to alcoholism.

Aplicação

Alcohol Dehydrogenase Activity Assay Kit has been used to determine the activity of alcohol dehydrogenase.

Adequação

Suitable for the detection of alcohol dehydrogenase in a variety of samples including tissue, cells and serum.

Princípio

The Alcohol Dehydrogenase Activity Assay kit provides a simple and direct procedure for measuring ADH activity in a variety of samples. ADH activity is determined using ethanol as the substrate in an enzyme reaction, which results in a colorimetric (450 nm) product proportional to the enzymatic activity present. One unit of ADH is the amount of enzyme that will generate 1.0 μmole of NADH per minute at pH 8.0 at 37 °C.

substituído por

Nº do produto
Descrição
Preços

Pictogramas

FlameExclamation mark
GHS02,GHS07

Palavra indicadora

Danger

Frases de perigo

H225 - H319 - H412

Classificações de perigo

Aquatic Chronic 3 - Eye Irrit. 2 - Flam. Liq. 2

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

53.6 °F - closed cup

Ponto de fulgor (°C)

12.0 °C - closed cup

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Kobi Simpson-Lavy et al.
Scientific reports, 9(1), 6491-6491 (2019-04-26)
Cells adapt their gene expression and their metabolism in response to a changing environment. Glucose represses expression of genes involved in the catabolism of other carbon sources in a process known as (carbon) catabolite repression. However, the relationships between "poor"
Rachel E N Reyes et al.
Brain research, 1747, 147067-147067 (2020-08-23)
Research focusing on the gut-brain axis is growing, but the interplay of ethanol (alcohol molecule), the gut microbiome, the brain and behavior is poorly understood. In the current study, we remodeled the gut microbiota by providing adult male C57BL/6J mice
Alcohol increases liver progenitor populations and induces disease phenotypes in human IPSC-derived mature stage hepatic cells
Tian L, et al.
International Journal of Biological Sciences, 12(9), 1052-1052 (2016)
Christopher M Ranger et al.
Proceedings of the National Academy of Sciences of the United States of America, 115(17), 4447-4452 (2018-04-11)
Animal-microbe mutualisms are typically maintained by vertical symbiont transmission or partner choice. A third mechanism, screening of high-quality symbionts, has been predicted in theory, but empirical examples are rare. Here we demonstrate that ambrosia beetles rely on ethanol within host
Sang-Hyuk Hong et al.
Phytotherapy research : PTR, 31(5), 783-791 (2017-03-17)
Although Pinus koraiensis leaf (PKL) was reported for its anti-diabetes, anti-obesity and anticancer effects as a folk remedy, the inhibitory effect of PKL on alcoholic fatty liver has never been elucidated yet. This study investigated the molecular mechanisms of PKL
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica