I4765

Human IgG4 Lambda, Recombinant Protein

purified immunoglobulin

• Sinônimo(s): Human IgG4 Protein
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: human (recombinant)
• Nível de qualidade: 200
• conjugado: unconjugated
• forma do anticorpo: purified immunoglobulin
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C

Descrição

Descrição geral

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections. IgG4 is the least abundant of the IgG subclass. IgG4-related systemic diseases include autoimmune pancreatitis, mediastinal fibrosis and multiple sclerosis.
IgG4, λ recombinant protein is obtained by expression of a phage library in a human cell line and purified by affinity chromatography.

Aplicação

The purified IgG4, λ may be used as an immunoglobulin calibrator, reference antigen, blocking agent, or coating protein in a variety of immunoassays including ELISA, dot blot immunobinding, Western immunobloting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell binding assays. Purified IgG4, λ was used as isotype control in flow cytometry of chronic lymphocytic leukemia and mantle cell lymphoma cells. It was also used for lectin- surface plasmon resonance and IgG subclass labelling by flow cytometry at a concentration of 50 μg/mL.

Nota de análise

The purity and identity are determined by immunoelectrophoresis, indirect ELISA, and SDS-PAGE.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable