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GW21143

Sigma-Aldrich

Anti-AP-1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Sinônimo(s):

Anti-Activator protein 1, Anti-Transcription factor AP-1

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About This Item

Número MDL:
MFCD02095845
Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

chicken

Nível de qualidade

200

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

Formulário

buffered aqueous solution

reatividade de espécies

mouse, human, rat

fabricante/nome comercial

Genway 15-288-21143

técnica(s)

western blot: suitable

nº de adesão NCBI

NP_002219.1

nº de adesão UniProt

P05412

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... JUN(3725)

Categorias relacionadas

Imunogênio

Immunogen Sequence: GI # 4758616, sequence 1-240
Recombinant V-jun avian sarcoma virus 17 oncogene homolog

Aplicação

Anti-AP-1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Ações bioquímicas/fisiológicas

c-Jun is a protein encoded by the JUN gene in humans. c-Jun in combination with c-Fos results in the formation of the AP-1 early response transcription factor. It is crucially involved in propagation of macrophage-driven inflammatory networks. AP1 may guide for the treatment decisions for endometriosis management and may provide a mechanistic endpoint for assessing efficacy of new agents aimed at curtailing inflammatory mechanisms that drive disease progression. It may possibly be utilized for the treatment of HPV-induced cervical cancers.

forma física

Solution in phosphate buffered saline containing 0.02% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificados de análise (COA)

Lot/Batch Number
049K0539
029K1730

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Sutapa Mahata et al.
Nutrition and cancer, 65 Suppl 1, 88-97 (2013-05-25)
Plant products of Phyllanthus emblica Linn. are traditionally consumed for its immense nutritive and medicinal values. However, the molecular mechanism(s) by which it exerts it effects is less understood. In this study, we investigated mechanism of action of P. emblica
Juling Lv et al.
International journal of clinical and experimental pathology, 11(8), 4221-4229 (2018-08-01)
Visible light has been previously demonstrated to induce retina damage and retinal ganglion cell (RGC) death through the mitochondrial pathway. The Fra-2 gene was detected as a transcriptional regulator, but whether it is involved in light-induced retina damage remains unclear.
Michael T Beste et al.
Science translational medicine, 6(222), 222ra16-222ra16 (2014-02-07)
Clinical management of endometriosis is limited by the complex relationship between symptom severity, heterogeneous surgical presentation, and variability in clinical outcomes. As a complement to visual classification schemes, molecular profiles of disease activity may improve risk stratification to better inform
Mohamed A Salem et al.
Scientific reports, 12(1), 6578-6578 (2022-04-23)
Aging has become a concern for many people, especially women. Given that high-quality anti-aging products are of high cost; it has imperative to search for other economical sources. Essential oils are frequently used in cosmetics products due to a wide

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