E1257

Epidermal Growth Factor from murine submaxillary gland

lyophilized powder, BioReagent, suitable for cell culture

• Sinônimo(s): EGF, Epidermal cell growth factor
• Número CAS: 62229-50-9
• Número CE: 263-468-7
• Número MDL: MFCD01634807
• Código UNSPSC: 12352202
• NACRES: NA.32

Propriedades

• fonte biológica: mouse submaxillary glands
• Nível de qualidade: 200
• linha de produto: BioReagent
• Ensaio: ≥98% (SDS-PAGE)
• forma: lyophilized powder
• potência: 0.02-2.0 ng/mL EC₅₀
• embalagem: pkg of 0.1 mg
• condição de armazenamento: avoid repeated freeze/thaw cycles
• técnica(s): cell culture | mammalian: suitable
• Impurezas: endotoxin, tested
• cor: white
• nº de adesão UniProt: P01132
• temperatura de armazenamento: 2-8°C
• Informações sobre genes: mouse ... Egf(13645)

Descrição

Descrição geral

Epidermal growth factor (EGF) is the member of EGF-like family of growth factors, that binds to EGF receptor. It is majorly expressed in kidney, parotid gland and salivary gland.

Aplicação

Epidermal Growth Factor from murine submaxillary gland has been used

• in studying its effects on the development of caustic esophageal stricture in rats
• for preparation of MCF-10A cell line
• for the culture of primary hair follicle stem cells from arbas cashmere goat (gHFSCs) and adhesion of hair follicles (HF)

Ações bioquímicas/fisiológicas

Epidermal growth factor (EGF) blocks gastric acid and pepsin secretion and increases gastrointestinal cell proliferation. EGF stimulates proliferation and migration in bone marrow stromal cells (BMSC), that gives rise to osteoblasts, chondrocytes and adipocytes. It functions as a strong mitogenic factor for various cultured cells. Mutations in this gene is linked to hypomagnesemia. EGF plays a major role in the maintenance of hair and skin development.

forma física

Lyophilized from 0.2 μm filtered solution in ammonium acetate buffer.

Nota de preparo

Purified by gel filtration and ion-exchange chromatography.

Nota de análise

The biological activity is measured in a proliferation assay using BALB/MK cells.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)