A8381

L-Asparagina

≥99% (TLC)

• Sinônimo(s): 4-Amida de ácido (S)-2-aminossuccínico, 4-Amida de ácido L-aspártico, Ácido (S)-(+)-2-aminossuccinâmico
• Fórmula linear: NH₂COCH₂CH(NH₂)COOH · H₂O
• Número CAS: 5794-13-8
• Peso molecular: 150.13
• Beilstein: 1723527
• Número CE: 200-735-9
• Número MDL: MFCD00151038
• Código UNSPSC: 12352209
• ID de substância PubChem: 24891338
• NACRES: NA.26

Propriedades

• product name: L-Asparagina, ≥99% (TLC)
• fonte biológica: synthetic
• Nível de qualidade: 200
• Ensaio: ≥99% (TLC)
• forma: powder
• cor: white to off-white
• pf: 233-235 °C (lit.)
• aplicação(ões): cell analysis; peptide synthesis
• cadeia de caracteres SMILES: [H]O[H].N[C@@H](CC(N)=O)C(O)=O
• InChI: 1S/C4H8N2O3.H2O/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H2,6,7)(H,8,9);1H2/t2-;/m0./s1
• chave InChI: RBMGJIZCEWRQES-DKWTVANSSA-N

Descrição

Descrição geral

Asparagine biosynthesis is catalyzed by glutamine-dependent asparagine synthetase in mammalian tissues. Elevated levels of free asparagine is observed in plants facing stress in the form of drought or high salt. It is also present in senescing leaves and germinating seeds.

Aplicação

L-Asparagine monohydrate has been used:

• as a component of Sauton′s and chelated Sauton′s media for mycobacterial growth
• to test its effect in the induction of Ca²⁺ flux in rice roots using aequorin luminescence imaging
• as a component of fermentation medium for the Blakeslea trispora spores

Ações bioquímicas/fisiológicas

Asparagine has high nitrogen to carbon ratio and is a key regulator for nitrogen storage and transport. Its thermal degradation in the presence of sugars leads to the acrylamide formation in foods. Asparagine serves as an amino acid exchange factor and is essential for amino acid homeostasis. It favors cancer cell proliferation.

L-Asparagine, a proteinogenic amino acid, is used in biomanufacturing cell culture systems for the production of therapeutic recombinant proteins and monoclonal antibodies and in cell culture based research.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)