483R-1

p40 (ZR8) Rabbit Monoclonal Antibody

• Código UNSPSC: 12352203

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100; 500
• conjugado: unconjugated
• forma do anticorpo: culture supernatant
• tipo de produto de anticorpo: primary antibodies
• clone: ZR8
• descrição: For In Vitro Diagnostic Use in Select Regions
• Formulário: buffered aqueous solution
• reatividade de espécies: human
• embalagem: vial of 0.1 mL concentrate (483R-14); vial of 0.1 mL concentrate, Research Use Only (483R-14-RUO); vial of 0.5 mL concentrate (483R-15); vial of 1.0 mL concentrate (483R-16); vial of 1.0 mL concentrate, Research Use Only (483R-16-RUO); vial of 1.0 mL pre-dilute, Research Use Only (483R-17-RUO); vial of 1.0 mL pre-dilute, ready to use (483R-17); vial of 25.0 mL pre-dilute, ready-to-use (483R-10); vial of 25.0 mL pre-dilute, ready-to-use, Research Use Only (483R-10-RUO); vial of 7.0 mL pre-dilute, ready to use (483R-18); vial of 7.0 mL pre-dilute, ready to use, Research Use Only (483R-18-RUO)
• fabricante/nome comercial: Cell Marque
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable (1:100-1:200 (concentrated))
• Isotipo: IgG
• controle: lung (squamous cell carcinoma), prostate, urothelial carcinoma
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C
• visualização: nuclear

Descrição

Descrição geral

p40 is an isoform of p63, a transcription factor that regulates many cell activities, including cell proliferation, maintenance, and differentiation. It performs as a sensitive and specific tool for aiding in the identification of squamous cell carcinoma of the lung. In addition to its utility as a squamous differentiation marker, p40 has also been proven to be a valuable marker for highlighting myoepithelial and basal cell populations in prostate, breast, skin, and salivary gland.^1-5 Strong p40 expression is frequently observed in esophageal cancerous squamous lesions.⁶ Immunohistochemical detection of p40 can also be helpful in identifying urothelial carcinoma.⁷ In cases of prostate carcinoma, p40 is almost always found to be negative for basal cell staining.⁸

Qualidade

• United States - IVD
• Canada - RUO
• European Union - IVD
• Japan - RUO

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota de preparo

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Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable