482R-1

p63 (EP174) Rabbit Monoclonal Primary Antibody

• Código UNSPSC: 12352203

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100; 500
• conjugado: unconjugated
• forma do anticorpo: culture supernatant
• tipo de produto de anticorpo: primary antibodies
• clone: EP174
• descrição: For In Vitro Diagnostic Use in Select Regions
• forma: buffered aqueous solution
• reatividade de espécies: human
• embalagem: vial of 0.1 mL concentrate (482R-14); vial of 0.1 mL concentrate, Research Use Only (482R-14-RUO); vial of 0.5 mL concentrate (482R-15); vial of 1.0 mL concentrate (482R-16); vial of 1.0 mL concentrate, Research Use Only (482R-16-RUO); vial of 1.0 mL pre-dilute ready-to-use, Research Use Only (482R-17-RUO); vial of 1.0 mL pre-dilute, ready to use (482R-17); vial of 25.0 mL pre-dilute ready-to-use (482R-10); vial of 25.0 mL pre-dilute ready-to-use, Research Use Only (482R-10-RUO); vial of 7.0 mL pre-dilute, ready to use (482R-18); vial of 7.0 mL pre-dilute, ready to use, Research Use Only (482R-18-RUO)
• fabricante/nome comercial: Cell Marque
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable (1:100-1:200 (concentrated))
• Isotipo: IgG
• controle: lung (squamous cell carcinoma), prostate
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C
• visualização: nuclear

Descrição

Descrição geral

p63 is a transcription factor that regulates many cell activities, including cell proliferation, maintenance, differentiation, adhesion, and apoptosis.¹ It has been found to be a sensitive and specific marker of myoepithelial and basal cell populations in prostate, breast, skin, and salivary gland. Additionally, p63 has also demonstrated immunohistochemical utility in identifying benign and malignant breast lesions.² In prostatic carcinomas, it can also be used to recognize benign glands adjacent to malignant glands.³ p63 can also be used to differentiate adenocarcinoma of the lungs, where it is usually negative, from squamous cell carcinoma, which can be useful for advanced stages of the carcinoma where surgery is no longer an option.⁴

Qualidade

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota de preparo

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Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2