426R-1

STAT6 (EP325) Rabbit Monoclonal Primary Antibody

• Sinônimo(s): Signal Transducer and Activator of Transcription
• Código UNSPSC: 12352203

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100; 500
• conjugado: unconjugated
• forma do anticorpo: culture supernatant
• tipo de produto de anticorpo: primary antibodies
• clone: EP325, monoclonal
• descrição: For In Vitro Diagnostic Use in Select Regions
• forma: buffered aqueous solution
• reatividade de espécies: human
• embalagem: vial of 0.1 mL concentrate (426R-14); vial of 0.1 mL concentrate Research Use Only (426R-14-RUO); vial of 0.5 mL concentrate (426R-15); vial of 1.0 mL concentrate (426R-16); vial of 1.0 mL concentrate Research Use Only (426R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (426R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (426R-17); vial of 7.0 mL pre-dilute ready-to-use (426R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (426R-18-RUO)
• fabricante/nome comercial: Cell Marque^™
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotipo: IgG
• controle: solitary fibrous tumor
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C
• visualização: nuclear
• Informações sobre genes: human ... STAT6(6778)

Descrição

Descrição geral

STAT6, a member of the signal transducers and activators of transcription (STAT) family, has been found to form recurrent fusions with NAB2 on chromosome 12q13 in the majority of solitary fibrous tumors. Inactivated STAT6 can be found in the form of a dimer located in the cytoplasm. STAT6 and NAB2 fusion enables cytosolic STAT6 to migrate to the nucleus and thus allowing for detection in immunohistochemical assays. NAB2-STAT6 fusion transcriptions have been reported in the majority of solitary fibrous tumors but not in meningiomas, hemangioblastomas, schwannomas, and hemangiomas. This makes STAT6 a useful marker in distinguishing solitary fibrous tumors from other morphologically similar tumors.

Qualidade

IVD

IVD

IVD

RUO

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota de preparo

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Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações legais

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable