370R-1

LMO2 (SP51) Rabbit Monoclonal Antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100; 500
• conjugado: unconjugated
• forma do anticorpo: culture supernatant
• tipo de produto de anticorpo: primary antibodies
• clone: SP51, monoclonal
• descrição: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formulário: buffered aqueous solution
• reatividade de espécies: human
• embalagem: vial of 0.1 mL concentrate (370R-14); vial of 0.5 mL concentrate (370R-15); bottle of 1.0 mL predilute (370R-17); vial of 1.0 mL concentrate (370R-16); bottle of 7.0 mL predilute (370R-18)
• fabricante/nome comercial: Cell Marque^®
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:2000
• Isotipo: IgG
• controle: diffuse large B-cell, follicular lymphoma
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C
• visualização: nuclear
• Informações sobre genes: human ... LMO2(4005)

Descrição

Descrição geral

LMO2 is expressed in normal germinal center B-cells and in a subset of lymphomas derived from those cells in addition to bone marrow hematopoietic precursors and endothelial cells. LMO2 protein expression has also been shown to play an important role in the diagnosis of diffuse large B-cell lymphomas, regardless of rituximab treatment. It also plays a role in angiogenesis and hematopoiesis. It is weakly expressed in mantle zone B-cells but not in mantle cell or marginal zone lymphomas. SF Younes et al. Have demonstrated LMO2 expression in 70% of follicular lymphomas. These data suggest that anti-LMO2 is a useful adjunct in the diagnosis of follicular lymphoma (FL). As LMO2 appears not to be down regulated in higher grade FL or the interfollicular and diffuse components of FL, its utility in variant immunoarchitectural patterns of FL and in cases that lack CD10 and bcl2, is similar to that of HGAL. One advantage of LMO2 is its crisp nuclear localization that allows for easier interpretation than diffuse cytoplasmic staining pattern.

Qualidade

IVD

IVD

IVD

RUO

Ligação

LMO2 Positive Control Slides, Product No. 370S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparo

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações legais

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable