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Sigma-Aldrich

Arsenic(III) oxide

ACS reagent (primary standard)

Sinônimo(s):

Arsenic trioxide, Arsenous acid

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About This Item

Fórmula empírica (Notação de Hill):
As2O3
Número CAS:
1327-53-3
Peso molecular:
197.84
Número CE:
215-481-4
Número MDL:
MFCD00003433
Código UNSPSC:
12171602
ID de substância PubChem:
329753664
NACRES:
NB.24
Ensaio:
99.95-100.05%
grau:
ACS reagent (primary standard)
Formulário:
powder
solubilidade:
dilute HCl: insoluble ≤0.01%

grau

ACS reagent (primary standard)

Nível de qualidade

200

pressão de vapor

0 hPa ( 66 °C)

Ensaio

99.95-100.05%

Formulário

powder

adequação da reação

reagent type: catalyst
core: arsenic

resíduo de ignição

≤0.02%

solubilidade

dilute HCl: insoluble ≤0.01%

traços de ânion

S2-: passes test (lim. ~0.001%)
chloride (Cl-): ≤0.005%

traços de cátion

Fe: ≤5 ppm
Pb: ≤0.002%
Sb: ≤0.05%

cadeia de caracteres SMILES

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

chave InChI

IKWTVSLWAPBBKU-UHFFFAOYSA-N

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Descrição geral

Arsenic (III) oxide, also referred to as arsenic trioxide, is an amphoteric oxide that is used as a raw material to produce several arsenic-based compounds.

Aplicação

Arsenic (III) oxide is used
  • In the synthesis of arsenic pentafluoride (AsF5) by static fluorination method in a closed system.
  • In the preparation of arsenic-doped ZnO films by adding As2O3 to zinc acetate, 2-methoxyethanol, and monoethanolamine by sol-gel spin coating method.

Palavra indicadora

Danger

Frases de perigo

H300,H314,H350,H372,H410

Classificações de perigo

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

Órgãos-alvo

Respiratory system,Cardio-vascular system,Gastrointestinal tract

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
MKCR0835
MKCQ1526
MKCP1816
MKCN7933
MKCN0837

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Sigma-Aldrich

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Supelco

72718

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Yanfei Jia et al.
PloS one, 8(1), e54774-e54774 (2013-02-06)
Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC), represented by the production of AFP, has a more aggressive behavior than common gastric cancer. The underlying mechanisms are not well understood. Arsenic trioxide (As(2)O(3)) is used clinically to treat acute promyelocytic leukemia(APL) and has
Liangchun Hao et al.
Journal of pediatric hematology/oncology, 35(2), e67-e70 (2013-02-16)
The aim of this study was to investigate the hepatotoxicity induced by arsenic trioxide (As2O3) at a therapeutic dose for pediatric acute promyelocytic leukemia (APL). A total of APL patients received As2O3 treatment by IV drip. Hepatotoxicity was monitored based
Yuhua Fan et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 31(1), 80-91 (2013-02-01)
Arsenic trioxide (As2O3) is a highly effective agent for treatment of acute promyelocytic leukemia (APL). However, consecutively administered As2O3 induces serious adverse cardiac effects, including long QT syndrome (LQTs) and even sudden cardiac death. Previous studies have shown that genistein
Huihui Wang et al.
Environmental toxicology, 28(5), 267-275 (2013-04-17)
Although arsenic is effective in the treatment of acute promyelocytic leukemia (APL), as a well-known environmental toxicant, the side effects of arsenic treatment and arsenic methylation metabolism of the patients are rarely reported. In this manuscript, we investigated 23 APL
Athena Kritharis et al.
Annals of hematology, 92(6), 719-730 (2013-03-16)
For more than 2,000 years, arsenic and its derivatives have shown medical utility. Owing to the toxicities and potential carcinogenicity of arsenicals, their popularity has fluctuated. The exact mechanism of action of therapeutic arsenic is not well characterized but likely
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