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Y0000054

Alprostadil

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

Prostaglandin E1, (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid, Alprostadil, PGE1

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About This Item

Fórmula empírica (Notação de Hill):
C20H34O5
Número CAS:
745-65-3
Peso molecular:
354.48
Beilstein:
5294062
Número CE:
212-017-2
Número MDL:
MFCD00077860
Código UNSPSC:
41116107
ID de substância PubChem:
329830830
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

alprostadil

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1

InChI

1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

chave InChI

GMVPRGQOIOIIMI-DWKJAMRDSA-N

Informações sobre genes

human ... PTGER1(5731) , PTGER2(5732)

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Alprostadil EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

produto relacionado

Nº do produto
Descrição
Preços

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H301

Declarações de precaução

P301 + P310 + P330

Classificações de perigo

Acute Tox. 3 Oral

Código de classe de armazenamento

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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J G Ray
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To assess whether prostaglandin E1 analogs have a role in either reducing renal allograft rejection or improving renal function among both transplant and nontransplant patients. Studies were identified through Ovid MEDLINE between 1981 and December 1997 using multiple MeSH headings
Michael Berner et al.
The journal of sexual medicine, 9(12), 3089-3107 (2012-10-24)
As yet, a summary of research evidence concerning the efficacy of psychological treatment in male sexual dysfunction is lacking. Our systematic review gives an overview of the efficacy of psychosocial interventions in all male sexual dysfunctions. Main outcome measures included
Mikkel Fode et al.
BJU international, 112(7), 998-1008 (2013-07-06)
The pathophysiology of erectile dysfunction after radical prostatectomy (RP) is believed to include neuropraxia, which leads to temporarily reduced oxygenation and subsequent structural changes in penile tissue. This results in veno-occlusive dysfunction, therefore, penile rehabilitation programmes focus on tissue oxygenation.
Yasuyuki Hara et al.
The Journal of surgical research, 184(2), 1134-1142 (2013-05-22)
To resolve the shortage of donors associated with liver transplantation, the potential uncontrolled non-heart-beating donor (UNHBD) pool is expected to increase. However, warm ischemia-reperfusion injury leads to inferior survival in transplantation using the grafts from UNHBD compared with those from
A Creutzig et al.
VASA. Zeitschrift fur Gefasskrankheiten, 33(3), 137-144 (2004-10-06)
The relevance of Prostaglandin El (PGE,) in the treatment of peripheral arterial occlusive disease stage III and IV was to be evaluated for the first time by a meta-analysis. Altogether, 643 patients were analyzed from seven randomized, controlled PGE1 studies
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