PHR1677

Anthralin (Dithranol)

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): Dithranol, 1,8,9-Anthracenetriol, 1,8-Dihydroxy-9(10H)-anthracenone, 1,8-Dihydroxyanthrone, Anthralin
• Fórmula empírica (Notação de Hill): C₁₄H₁₀O₃
• Número CAS: 1143-38-0
• Peso molecular: 226.23
• Beilstein: 2054360
• Número CE: 214-538-0
• Número MDL: MFCD00053409
• Código UNSPSC: 41116107
• ID de substância PubChem: 329823549
• NACRES: NA.24

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to Ph. Eur. D2953000; traceable to USP 1039006
• família API: anthralin, dithranol
• Certificado de análise (CofA): current certificate can be downloaded
• embalagem: pkg of 1 g
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• pf: 178-181 °C (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• Formato: neat
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: Oc1cccc2Cc3cccc(O)c3C(=O)c12
• InChI: 1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2
• chave InChI: NUZWLKWWNNJHPT-UHFFFAOYSA-N

Descrição

Descrição geral

Anthralin (Dithranol) is the synthetic form of chrysarobin. It is widely used as a medication for the human skin affected with psoriasis and in short contact therapy to minimize the staining, irritation, etc.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Anthralin (Dithranol) may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high pressure liquid chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA6122 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319,H335
• Declarações de precaução: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable