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PHR1433

Supelco

Ascorbyl Glucoside

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

Ascorbyl Glucoside

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About This Item

Fórmula empírica (Notação de Hill):
C12H18O11
Número CAS:
129499-78-1
Peso molecular:
338.26
Número MDL:
MFCD23701380
Código UNSPSC:
41116107
ID de substância PubChem:
329822597
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

300

família API

ascorbyl glucoside

Formulário

solid

Certificado de análise (CofA)

current certificate can be downloaded

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

OC([C@]([C@@H](O)CO)([H])O1)=C(C1=O)O[C@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO

InChI

1S/C12H18O11/c13-1-3(15)9-8(19)10(11(20)22-9)23-12-7(18)6(17)5(16)4(2-14)21-12/h3-7,9,12-19H,1-2H2/t3-,4+,5+,6-,7+,9+,12+/m0/s1

chave InChI

MLSJBGYKDYSOAE-DCWMUDTNSA-N

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Descrição geral

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ascorbyl Glucoside is used to protect skin from exposure to UV rays.

Aplicação

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA2741 in the slot below. This is an example certificate only and may not be the lot that you receive.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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The stable ascorbic acid derivative 2-O-alpha-D-glucopyranosyl-L-ascorbic acid (AA-2G) was used to investigate the role of ascorbic acid (AA) in B cell differentiation in vitro. AA-2G is stable in a solution unlike AA but is hydrolyzed by cellular alpha-glucosidase to release
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6-O-dodecanoyl-2-O-α-D-glucopyranosyl-L-ascorbic acid (6-sDode-AA-2G) was synthesized from 2-O-α-D-glucopyranosyl-L-ascorbic acid and vinyl laurate with a protease from Bacillus subtilis in 30% dimethylformamide (DMF)/dioxane with a low water content. The addition of 3% (v/v) water to DMF/dioxane dramatically enhanced the 6-sDode-AA-2G synthesis. The
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2-O-alpha-D-glucopyranosyl-L-ascorbic acid (AA2G) is a stable glycoside, but its conversion to bioavailable ascorbic acid (AsA) in humans remains unknown. The aim of this study was to clarify that AA2G is hydrolyzed by human intestinal maltase and AA2G by oral ingestion
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