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H0800000

Homatropine hydrobromide

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

DL-Homatropine hydrobromide, DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide, Tropine mandelate hydrobromide

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About This Item

Fórmula empírica (Notação de Hill):
C16H21NO3 · HBr
Número CAS:
51-56-9
Peso molecular:
356.25
Número MDL:
MFCD00012676
Código UNSPSC:
41116107
ID de substância PubChem:
329815135
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

homatropine

fabricante/nome comercial

EDQM

pf

214-217 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Br.CN1C2CCC1CC(C2)OC(=O)C(O)c3ccccc3

InChI

1S/C16H21NO3.BrH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H

chave InChI

DWSGTFTVBLXELC-UHFFFAOYSA-N

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Descrição geral

Homatropine hydrobromide is an anticholinergic agent and is commonly used as a mydriatic and cycloplegic drug in ophthalmology.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Brian M Thome et al.
Journal of chromatography. A, 1138(1-2), 291-300 (2006-11-14)
Over the past decade the moving bed process has become a commonly used tool for the continuous separation of chiral compounds, and its recent application to electrophoretic separations allows the technique to be used as a model system for moving
Homatropine and psychosis in Weill-Marchesani syndrome.
Anjaiah Madugula et al.
Journal of the American Academy of Child and Adolescent Psychiatry, 45(7), 769-770 (2006-07-13)
Determination of homatropine hydrobromide in eye drops by second-order derivative spectroscopy.
Leung C P, et al.
Journal of Pharmaceutical and Biomedical Analysis, 9(2), 195-198 (1991)
Bhavna Chawla et al.
International ophthalmology, 29(1), 53-55 (2007-11-17)
To report a case of peripheral ulcerative keratitis (PUK) and scleritis, along with bilateral optic nerve infiltration as an initial presentation of acute lymphocytic leukemia (ALL) in an adult. Observational case report. A 24-year-old patient presented with complaints of pain
Robert Meek et al.
Emergency medicine Australasia : EMA, 22(6), 507-513 (2010-12-15)
To compare the change in visual analogue scale (VAS) pain ratings over 24 h following mechanical corneal abrasion between patients receiving sixth hourly drops of either 5% homatropine or placebo. A triple blind randomized controlled trial was conducted on a
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