BP587

Fluticasone propionate

British Pharmacopoeia (BP) Reference Standard

• Sinônimo(s): (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-(fluoromethyl) ester
• Fórmula empírica (Notação de Hill): C₂₅H₃₁F₃O₅S
• Número CAS: 80474-14-2
• Peso molecular: 500.57
• Número MDL: MFCD00866007
• Código UNSPSC: 41116107
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: fluticasone
• forma: solid
• prazo de validade: limited shelf life, expiry date on the label
• fabricante/nome comercial: BP
• aplicação(ões): pharmaceutical; pharmaceutical small molecule
• formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
• InChI: 1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
• chave InChI: WMWTYOKRWGGJOA-CENSZEJFSA-N
• Informações sobre genes: human ... NR3C1(2908)

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Fluticasone propionate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Fluticasone and Salmeterol Inhalation Powder

Fluticasone and Salmeterol Inhalation Powder, pre-metered

Fluticasone Nasal Spray

Fluticasone and Salmeterol Pressurised Inhalation, Suspension

Fluticasone Pressurised Inhalation

Fluticasone Nasal Drops

Fluticasone Cream

Fluticasone Inhalation Powder

Fluticasone Ointment

Fluticasone Inhalation Powder, pre-metered

Ações bioquímicas/fisiológicas

Fluticasone propionate is a second generation glucocorticoid. Used as an anti-inflammatory agent for asthma. Shown to enhance eosinophil apoptosis in a concentration-dependent manner via the glucocorticoid receptor.

Embalagem

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Warning
• Frases de perigo: H361f,H373
• Declarações de precaução: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Classificações de perigo: Repr. 2 - STOT RE 2
• Órgãos-alvo: Endocrine system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable