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A5144

Sigma-Aldrich

8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate

≥95% purity (perchloric acid titration), for fluorescence, powder

Sinônimo(s):

1,8-ANS magnesium salt, ANSA magnesium salt, Magnesium 8-anilino-1-naphthalenesulfonate hydrate, N-Phenyl peri acid magnesium salt

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About This Item

Fórmula empírica (Notação de Hill):
C16H12Mg0.5NO3S · xH2O
Número CAS:
18108-68-4
Peso molecular:
310.49 (anhydrous basis)
Beilstein:
4834623
Número CE:
242-004-7
Número MDL:
MFCD16661224
Código UNSPSC:
12171500
ID de substância PubChem:
329770870
NACRES:
NA.47

product name

8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate, for fluorescence, ≥95% (TLC)

grau

for fluorescence

Nível de qualidade

200

Ensaio

≥95% (TLC)

forma

powder

cor

faint green to green

solubilidade

H2O: 50 mg/mL

aplicação(ões)

diagnostic assay manufacturing
hematology
histology

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

O.[Mg++].[O-]S(=O)(=O)c1cccc2cccc(Nc3ccccc3)c12.[O-]S(=O)(=O)c4cccc5cccc(Nc6ccccc6)c45

InChI

1S/2C16H13NO3S.Mg.H2O/c2*18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13;;/h2*1-11,17H,(H,18,19,20);;1H2/q;;+2;/p-2

chave InChI

FBANPIUXAXTAFX-UHFFFAOYSA-L

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Descrição geral

ANSA (8-Anilino-1-naphthalenesulfonic acid) is a hydrophobic polarity sensitive fluorescent dye useful as a site probe to detect conformational changes in cell and micelle membranes and molecules such as proteins. ANSA is also used as a fluorescent probe for the estimation of the critical micelle concentration (CMC) of surfactants.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
BCCC9822
BCCC9496
BCCC9821
BCCB6061
BCBT3783

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Chang Li et al.
International journal of biological macromolecules, 49(5), 910-916 (2011-08-23)
In our study, we showed that at a relatively low concentration, H(2)O(2) can irreversibly inactivate the human brain type of creatine kinase (HBCK) and that HBCK is inactivated in an H(2)O(2) concentration-dependent manner. HBCK is completely inactivated when incubated with
V G Artyukhov et al.
Bulletin of experimental biology and medicine, 153(6), 907-911 (2012-11-01)
Structural and functional state of human blood lymphocytes after exposure to UV light (240-390 nm) in doses of 151-1359 J/m(2) was studied by methods of laser flow cytofluorometry, indirect immunofluorescence, and fluorescent probes. Using a combination of these methods, we
Clare A Peters Libeu et al.
PloS one, 7(6), e40027-e40027 (2012-07-07)
One of the events associated with Alzheimer's disease is the dysregulation of α- versus β-cleavage of the amyloid precursor protein (APP). The product of α-cleavage (sAPPα) has neuroprotective properties, while Aβ1-42 peptide, a product of β-cleavage, is neurotoxic. Dimerization of
James A McLure et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(9), 1711-1717 (2011-05-26)
The fluorescence of 1-anilinonaphthalene-8-sulfonate (ANS) in the presence of human liver microsomes (HLMs) is altered by drugs that bind nonspecifically to the lipid bilayer. The present study characterized the relationship between the nonspecific binding (NSB) of drugs to HLMs as
Stefan Kofler et al.
Journal of molecular biology, 422(1), 109-123 (2012-05-29)
The ability of pathogenesis-related proteins of family 10 to bind a broad spectrum of ligands is considered to play a key role for their physiological and pathological functions. In particular, Bet v 1, an archetypical allergen from birch pollen, is
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