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81210

Sigma-Aldrich

Poli(etilenoglicol)

average Mw 1,500

Sinônimo(s):

PEG

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About This Item

Fórmula linear:
H(OCH2CH2)nOH
Número CAS:
25322-68-3
Número MDL:
MFCD00081839
Código UNSPSC:
12352104
ID de substância PubChem:
24887690
NACRES:
NA.23

Nome do produto

Poli(etilenoglicol), average Mw 1,500

Formulário

solid

Nível de qualidade

200

peso molecular

average Mw 1,500

pf

45-50 °C

temperatura de transição

Tm 45-50 °C

Ω-final

hydroxyl

α-final

hydroxyl

cadeia de caracteres SMILES

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

chave InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Descrição geral

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, required for the purification of biological materials. PEG also interacts with cell membrane, thereby resulting in cell fusion.

Aplicação

Poly(ethylene glycol) has been used for histological, histochemical and immunohistochemical evaluation of in vitro cultured beads. It has been used for the fusion of cells.

Outras notas

Molecular weight range: 1,400-1,600

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
BCCD3122
BCCB0461
BCBX5256
BCBW2779
BCBT9003

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Chondrogenesis of human mesenchymal stem cells encapsulated in alginate beads.
Ma HL et al.
Journal of Biomedical Materials Research Part A, 64, 273-273 (2003)
Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
Angewandte Chemie (International Edition in English), 49, 6288-6308 (2010)
DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-beta, and anti-inflammatory agents.
Relloso M et al.
Journal of Immunology, 168, 2634-2634 (2002)
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
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Artigos

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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