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Documentos Principais

00200595

Quercetin dihydrate

primary reference standard

Sinônimo(s):

2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate, 3,3′,4′,5,7-Pentahydroxyflavone dihydrate

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About This Item

Fórmula empírica (Notação de Hill):
C15H10O7 · 2H2O
Número CAS:
Peso molecular:
338.27
Número do índice de cores:
75670
Beilstein:
317313
Número CE:
Código UNSPSC:
85151701
NACRES:
NA.24

grau

primary reference standard

Formulário

powder

prazo de validade

limited shelf life, expiry date on the label

fabricante/nome comercial

HWI

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

>300 °C (lit.)

cadeia de caracteres SMILES

OC(C(O)=C1)=CC=C1C2=C(O)C(C3=C(O)C=C(O)C=C3O2)=O

InChI

1S/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2

chave InChI

GMGIWEZSKCNYSW-UHFFFAOYSA-N

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Descrição geral

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Aplicação

Reference standard in the analysis of herbal medicinal products.

Ações bioquímicas/fisiológicas

Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

Outras notas

This compound is commonly found in plants of the genus: allium angelica arnica carum echinacea eucalyptus ginkgo glycyrrhiza lycium pimpinella primula sambucus silybum

Pictogramas

Skull and crossbones

Palavra indicadora

Danger

Frases de perigo

Declarações de precaução

Classificações de perigo

Acute Tox. 3 Oral

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 1


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Reactive oxygen species play a role in a number of degenerative conditions including osteoporosis. Flavonoids as phyto-oestrogens exert physiological effects against oxidative stress diseases. We developed a retinoic acid-induced bone loss model of rats to assess whether flavonoids and alendronate
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This study was designed to evaluate the effect of quercetin, a natural flavonoid, on behavioral alterations, brain oxidative stress, and immune dysregulation caused by a chemotherapeutic agent, Adriamycin (ADR; 7 mg/kg of body weight). Different subsets of male Wistar rats were
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