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00190585

Hypericin

primary reference standard

Sinônimo(s):

4,5,7,4′,5′,7′-Hexahydroxy-2,2′-dimethylnaphthodianthrone

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About This Item

Fórmula empírica (Notação de Hill):
C30H16O8
Número CAS:
548-04-9
Peso molecular:
504.44
Beilstein:
1917913
Número CE:
208-941-0
Número MDL:
MFCD00016683
Código UNSPSC:
85151701
ID de substância PubChem:
329747015
NACRES:
NA.24

grau

primary reference standard

prazo de validade

limited shelf life, expiry date on the label

fabricante/nome comercial

HWI

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

Cc1cc(O)c2C(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6C(=O)c7c(O)cc(C)c8c1c2c(c34)c(c78)c56

InChI

1S/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,31-36H,1-2H3

chave InChI

BTXNYTINYBABQR-UHFFFAOYSA-N

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Descrição geral

Produced by HWI Analytik
Exact content can be found on the certificate

Aplicação

It was used as reference standard in determining hypericins in St. John′s Wort using HPLC method.
Reference standard in the analysis of herbal medicinal products.

Outras notas

This compound is commonly found in plants of the genus: hypericum

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302

Declarações de precaução

P264 - P270 - P301 + P312 - P501

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
HWI02819-1
HWI02819
HWI02062-1
HWI02062
HWI01814-2

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D E Gray et al.
Journal of AOAC International, 83(4), 944-949 (2000-09-20)
Hypericin and hyperforin are believed to be among the active constituents in common St. John's wort (Hypericum perforatum L.). Presently, dietary supplements are generally standardized to contain specified levels of hypericin and hyperforin, and the related compounds, pseudohypericin and adhyperforin.
J B Hudson et al.
Antiviral research, 15(2), 101-112 (1991-02-01)
Hypericin, a photodynamic plant quinone, readily inactivated murine cytomegalovirus (MCMV), Sindbis virus, and human immunodeficiency virus type 1 (HIV-1), especially on exposure to fluorescent light. Sindbis virus was significantly more sensitive than MCMV. The inactivated MCMV, when used to infect
Theodossis A Theodossiou et al.
Molecular pharmaceutics, 6(6), 1775-1789 (2009-09-11)
Photodynamic therapy (PDT) is an established anticancer treatment employing a phototoxin (photosensitizer), visible light and oxygen. The latter is photochemically converted into reactive oxygen species, which are highly toxic to the cells. Hypericin, a natural pigment of hypericum plants, is
Pavol Miskovsky
Current drug targets, 3(1), 55-84 (2002-03-20)
Hypericin, a naturally occurring pigment, is found in certain species of plants from the genus Hypericum, the most common of which is Saint John's Wort (Hypericum perforatum). Recent interest in hypericin is provoked by the discovery that it possesses extremely
Tobias Kiesslich et al.
Current medicinal chemistry, 13(18), 2189-2204 (2006-08-22)
During the last decades, Photodynamic Therapy (PDT) has been established as a powerful alternative approved by health agencies of several countries for treatment of various malignant and some non-malignant diseases. PDT makes use of the light-induced destruction of target cells
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