MABC127

Anti-Ephrin-B2 Antibody

clone 10H1.1, from mouse

• Sinônimo(s): Ephrin-B2, EPH-related receptor tyrosine kinase ligand 5, LERK-5, HTK ligand, HTK-L
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: 10H1.1, monoclonal
• reatividade de espécies: mouse, rat, human
• técnica(s): immunohistochemistry: suitable; western blot: suitable
• Isotipo: IgMκ
• nº de adesão NCBI: NP_004084
• nº de adesão UniProt: P52799
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... EFNB2(1948)

Descrição

Descrição geral

Ephrin-B2 is also called EPH-related receptor tyrosine kinase ligand 5 (LERK-5) and HTK ligand (HTK-L). Ephrin-B2 is a cell surface transmembrane ligand for the Eph tyrosine kinase family of receptors. Ephrin-B2 binds Eph receptors on adjacent cells, leading to contact-dependent bidirectional signaling, which is critical for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Ephrin-B2 is expressed in lung and kidney and together with EPHB4 is involved in heart morphogenesis and angiogenesis.

Imunogênio

KLH-conjugated linear peptide corresponding to human Ephrin-B2.

Aplicação

Anti-Ephrin-B2, clone 10H1.1, Cat. No. MABC127, is a mouse monoclonal antibody that detcets Ephrin-B2 and has been tested for use in immunohitochemistry and Western Blotting.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Western Blotting Analysis: 0.5 µg/mL from a representative lot detected Ephrin-B2 in rat and human lung tissue lysate.

Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Ephrin-B2 in IHC.

Qualidade

Evaluated by Western Blotting in mouse lung tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Ephrin-B2 in 10 µg of mouse lung tissue lysate.

Descrição-alvo

~65 kDa observed. The calculated molecular weight of this protein is ~37 kDa; however, this protein has been observed at 65-70 kDa (Attwood, B. K., et al. (2011). Nature. 473(7347):372–375.; Lin, K. T., et al. (2008). J Biol Chem. 283(43):28969-28979.).

forma física

Format: Purified

Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Nota de análise

Control
Mouse lung tissue lysate

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable