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Documentos Principais

MAB5596

Sigma-Aldrich

Anti-HCN2 Antibody

culture supernatant, Chemicon®

Sinônimo(s):

Hyperpolarization-activated and cyclic nucleotide-gated channel 2

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
clone:
monoclonal
application:
IHC
WB
reatividade de espécies:
mouse, rat
técnica(s):
immunohistochemistry: suitable
western blot: suitable
citations:
2

fonte biológica

rat

Nível de qualidade

100

forma do anticorpo

culture supernatant

tipo de produto de anticorpo

primary antibodies

clone

monoclonal

reatividade de espécies

mouse, rat

fabricante/nome comercial

Chemicon®

técnica(s)

immunohistochemistry: suitable
western blot: suitable

Isotipo

IgG1

nº de adesão NCBI

NM_001194.3

nº de adesão UniProt

Q9UL51

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

mouse ... Hcn2(15166)
rat ... Hcn2(114244)

Especificidade

HCN2 (Hyperpolarization-activated and cyclic nucleotide-gated channel 2). The antibody recognizes both the glycosyated and deglycosylated form of HCN2. The antibody recognizes a weak band at ~98 kDa and a stronger band at ~108 kDa in glycosylated protein from a retinal membrane preparation.

Imunogênio

Synthetic peptide from rat HCN2.

Aplicação

Anti-HCN2 Antibody is an antibody against HCN2 for use in IH & WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
Western blot on rat and mouse retina. The antibody recognizes a weak band at ~98 kDa and a stronger band at ~108 kDa in glycosylated protein from a retinal membrane preparation.

Immunohistochemistry on rat and mouse retina.

Optimal working dilutions must be determined by end user.

forma física

Cultured supernatant containing 0.05% sodium azide.

Armazenamento e estabilidade

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Frank Müller et al.
The European journal of neuroscience, 17(10), 2084-2096 (2003-06-06)
Hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels codetermine the integrative behaviour of neurons and shape their response to synaptic stimulation. We used immunohistochemistry and patch-clamp recording to study the composition and distribution of HCN channels in the rat retina. All four
Joon Ha Park et al.
International journal of molecular medicine, 44(5), 1801-1810 (2019-10-02)
Hyperpolarization‑activated cyclic nucleotide‑gated (HCN) channels have been known to participate in the regulation of neuronal excitability, synaptic transmission and long‑term potentiation in the hippocampus. The present study investigated transient ischemia‑induced changes of HCN1 and HCN2 expressions in the Cornu Ammonis
Stuart M Cain et al.
Pflugers Archiv : European journal of physiology, 467(6), 1367-1382 (2014-06-24)
Burst-firing in distinct subsets of thalamic relay (TR) neurons is thought to be a key requirement for the propagation of absence seizures. However, in the well-regarded Genetic Absence Epilepsy Rats from Strasbourg (GAERS) model as yet there has been no

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