Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

MAB3230

Sigma-Aldrich

Anti-Cytokeratin 10 Antibody, clone RKSE60

clone RKSE60, Chemicon®, from mouse

Faça loginpara ver os preços organizacionais e de contrato


About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

forma do anticorpo

purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

RKSE60, monoclonal

reatividade de espécies

rat, canine, human, mouse

fabricante/nome comercial

Chemicon®

técnica(s)

flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

Isotipo

IgG1

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... KRT10(3858)

Descrição geral

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight from between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8, The individual cytokeratin polypeptides are designated 1-20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies.

Especificidade

Cytokeratin 10. MAB3230 reacts with keratinizing stratified epithelia and in differentiated areas of highly differentiated squamous cell carcinomas. For the recognition of keratinizing cells in squamous cell carcinomas from epidermis, lung, bladder, cervix, esophagus etc. The antibody reacts only with suprabasal cells of the epidermis and not with basal cells.

Imunogênio

Cytoskeletal preparation from human squamous keratinizing epithelium.

Aplicação

Anti-Cytokeratin 10 Antibody, clone RKSE60 detects level of Cytokeratin 10 & has been published & validated for use in FC, WB, IC, IH.
Research Category
Cell Structure
Research Sub Category
Cytokeratins
Western blot

Immunohistochemistry on frozen tissue sections.

Immunocytochemistry

Flow cytometry

Optimal working dilutions must be determined by the end user.

forma física

Format: Purified
Liquid in buffer with 0.1% sodium azide.

Armazenamento e estabilidade

Maintain at -20°C in undiluted aliquots up to 6 months. Avoid repeated freeze/thaw cycles.

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Não está encontrando o produto certo?  

Experimente o nosso Ferramenta de seleção de produtos.

Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation.
Nana Naetar,Barbara Korbei,Serguei Kozlov,Marc A Kerenyi,Daniela Dorner,Rosana Kral et al.
Nature Cell Biology null
Atsushi Tokuriki et al.
Carcinogenesis, 30(9), 1645-1650 (2009-07-10)
Inhibitor of DNA binding 2 (Id2) is a negative regulator of basic helix-loop-helix transcription factors and is involved in the control of cellular differentiation and proliferation. By using a two-step chemical carcinogenesis protocol, we evaluated the role of Id2 in
Masashi Miyai et al.
The Journal of investigative dermatology, 136(9), 1848-1857 (2016-05-22)
Mammalian epidermis is a stratified epithelium composed of distinct layers of keratinocytes. The outermost cornified layer is a primary barrier that consists of a cornified envelope, an insoluble structure assembled by cross-linked scaffold proteins, and a surrounding mixture of lipids.
Inflammatory marker analysis in psoriatic skin under topical phosphodiesterase 4 inhibitor treatment.
Lennart M Roesner et al.
The Journal of allergy and clinical immunology, 140(4), 1184-1187 (2017-05-17)
Ryo Ichijo et al.
Nature communications, 8(1), 508-508 (2017-09-13)
The skin surface area varies flexibly in response to body shape changes. Skin homeostasis is maintained by stem cells residing in the basal layer of the interfollicular epidermis. However, how the interfollicular epidermal stem cells response to physiological body shape

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica