HIFN-130K-PMX9

MILLIPLEX^® Human Interferon Panel 9-Plex Premix

• Sinônimo(s): Human Cytokine Panel
• Código UNSPSC: 12161503
• NACRES: NA.77

Propriedades

• uso: -1 kit -96 wells
• Nível de qualidade: 200
• reatividade de espécies: human
• fabricante/nome comercial: Milliplex^®
• Parâmetros: -25 μL sample volume (per well)
• método de detecção: fluorometric (Luminex^® xMAP^®)
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C

Descrição

Descrição geral

Interferons (IFNs) are widely expressed cytokines that have potent antiviral and antiproliferative effects. These cytokines are the first line of defense against viral infections and have important roles in immunosurveillance for malignant cells. IFNs are classified as type I, II and III IFNs, based upon the target receptors to which they bind. In humans, type I IFNs belong to a multigene family consisting of multiple IFNα subtypes but only one IFNβ, IFNε, IFNκ, and IFNω. There is only one type II IFN: IFNγ. The type III IFNs include IFNλ1, λ2 and λ3, which are also known as interleukin-29 (IL-29), IL 28A and IL-28B, respectively. Functionally, the type I and type III IFNs are induced during a viral infection and involved in host defense against viruses. IFNγ (type II) is primarily involved in the allergic response, in host defense against intracellular pathogens, and in control of tumor growth. Studies of IFNs have broadened the mechanistic understanding of cell signaling, gene transcription, and innate and acquired immunity.

Research category: Inflammation & Immunology

Research sub-category:

• Inflammation & Autoimmune Mechanisms
• Inflammation

Especificidade

There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.

Aplicação

The MILLIPLEX^® Human Interferon Magnetic Bead Panel is a 9-plex kit to be used for the simultaneous quantification of the following analytes in serum or plasma samples and tissue/cell lysate and culture supernatant samples: IFNα-2, IFNβ, IFNε, IFNɣ, IFNɣ Receptor 1, IFNλ1, IFNλ2, IFNλ3, IFNω.

Características e benefícios

Design your multiplex kit by choosing available analytes within this panel.

Informações legais

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Pictogramas: GHS06,GHS08,GHS05,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H302 + H332,H311,H317,H318,H373,H411
• Declarações de precaução: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• Órgãos-alvo: Respiratory Tract
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable