FCMAB188F

Milli-Mark^® Anti-CD24-FITC Antibody, clone SN3

clone SN3, Milli-Mark^®, from mouse

• Sinônimo(s): Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• conjugado: FITC conjugate
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: SN3, monoclonal
• reatividade de espécies: human
• fabricante/nome comercial: Milli-Mark^®
• técnica(s): flow cytometry: suitable
• Isotipo: IgG1κ
• nº de adesão NCBI: NP_037362.1
• nº de adesão UniProt: P25063
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... CD24(100133941)

Descrição

Descrição geral

The CD24 antigen, which has a molecular weight of 35-45 kDa, is a glycosyl phosphatidylinositol (GPI)-anchored surface molecule. It is a member of a family that also includes HSA and CD52. Cross-linking of CD24 can induce increased intracellular Ca++ in mature B lymphocytes (Turni, 2002).
CD24 is expressed at multiple stages of B cell development, beginning with the bone marrow CD34+ pro-B-cell compartment and continuing through mature surface IgM+/IgD+ B cells. Plasma cells express very low to negligible levels of CD24 (Le Bien, 1995). CD24 is not expressed on the cell surface of normal T cells or monocytes, but is expressed on mature granulocytes (Le Bien, 1995; Fukukawa, 1986). The antigen is also present on a variety of epithelial types (Turni, 2002).

Especificidade

Antibody recognizes Human CD24 antigen.

Imunogênio

Isolated membrane fraction of the pre-B leukemic cell line NALM-1.

Aplicação

Detect CD24 using this Milli-Mark Anti-CD24-FITC Antibody, clone SN3 validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Qualidade

Evaluated by flow cytometry using human PBMCs

Descrição-alvo

35-45 kDa (Turni, 2002)

forma física

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Armazenamento e estabilidade

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Nota de análise

Control
PBMCs

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações legais

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable