About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Produtos recomendados
fonte biológica
chicken
Nível de qualidade
Formulário
liquid
fabricante/nome comercial
Chemicon®
concentração
100 μg/mL
técnica(s)
ELISA: suitable
cell culture | mammalian: suitable
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
dry ice
Informações sobre genes
chicken ... NCAN(395493)
Descrição geral
Neurocan, chicken.
Product Source: Chicken Brain.
Aplicação
Inhibition of cell-cell adhesion, cell-ECM adhesion or cell migration at:
0.1 to 30 micrograms / mL.
ELISA Assay: 0.05 to 5 micrograms / mL
Optimal working concentrations must be determined by the end user.
0.1 to 30 micrograms / mL.
ELISA Assay: 0.05 to 5 micrograms / mL
Optimal working concentrations must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
forma física
Purified Neurocan in PBS. Contains no preservative.
Armazenamento e estabilidade
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Nota de análise
A mix of Chondroitin Sulfate Proteoglycans from chick brain (Chemicon CC117) was purified by the unique density and size of this class of molecules. Neurocan is purified from this mix using an immobilized monoclonal antibody. The resulting neurocan is pure and has chondroitin sulfate attached. Removing the chondroitin sulfate with chondroitinase, results in core proteins are primarily the full-length 250 kD form and a little of smaller neurocan fragments.
Informações legais
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
H Ernst et al.
Journal of cell science, 108 ( Pt 12), 3807-3816 (1995-12-01)
Chondroitin sulfate proteoglycans inhibit the adhesion of cells to extracellular matrix proteins that otherwise permit adhesion. Although proteoglycans are widely assumed to act by masking the other protein in a mixed substrate, recent studies suggest that proteoglycans inhibit adhesion through
The interaction of the retina cell surface N-acetylgalactosaminylphosphotransferase with an endogenous proteoglycan ligand results in inhibition of cadherin-mediated adhesion.
Balsamo, J, et al.
The Journal of cell biology, 129, 1391-1401 (1995)
MMP and non-MMP-mediated release of aggrecan and its fragments from articular cartilage: a comparative study of three different aggrecan and glycosaminoglycan assays.
E U Sumer, B C Sondergaard, J C Rousseau, P D Delmas, A J Fosang, M A Karsdal et al.
Osteoarthritis and Cartilage / OARS, Osteoarthritis Research Society null
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