ABT272

Anti-SUN2 Antibody

from rabbit, purified by affinity chromatography

• Sinônimo(s): SUN domain-containing protein 2, Protein unc-84 homolog B, Rab5-interacting protein, Rab5IP, Sad1/unc-84 protein-like 2
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• purificado por: affinity chromatography
• reatividade de espécies: mouse, human
• técnica(s): immunocytochemistry: suitable; western blot: suitable
• nº de adesão NCBI: NP_001186508
• nº de adesão UniProt: Q9UH99
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... SUN2(25777)

Descrição

Descrição geral

SUN domain-containing protein 2 (SUN2), or Protein UNC-84 homolog B (UNC84B), is a single-pass nuclear envelope transmembrane protein responsible for nuclear migrations that are essential for development. SUN2 has a predicted transmembrane domain and a C-terminal region with similarity to the S. pombe spindle pole body protein Sad1. SUN2 interacts with RAB5A and is widely expressed, and highly expressed in the heart, lungs and muscles. UNC-84 may function to facilitate a nuclear-centrosomal interaction required for nuclear migration and anchorage.

Imunogênio

Epitope: N-terminus

Linear peptide corresponding to the N-terminus of human Sun2.

Aplicação

Detect SUN2 using this Anti-SUN2 antibody validated for use in western blotting & ICC.

Research Category
Cell Structure

Research Sub Category
Adhesion (CAMs)

Western Blotting Analysis: A 1:500 dilution from a representative lot detected SUN2 in 10 µg of A431, Jurkat, L6, and NIH/3T3 cell lysate.
Western Blotting Analysis: A representative lot detected SUN2 recombinant protein (Haque, F., et al. (2010). Journal of Biol. Chem. 285(5): 3487-3498).
Immunocytochemistry Analysis: A representative lot detected SUN2 in human foreskin fibroblasts and NIH/3T3 cells (Haque, F., et al. (2010). Journal of Biol. Chem. 285(5): 3487-3498).

Qualidade

Evaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected SUN2 in 10 µg of HEK293 cell lysate.

Descrição-alvo

~ 78 kDa observed. Uncharacterized band(s) may appear in some lysates.

forma física

Affinity purified

Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable