ABS445

Anti-Caspase-5 Antibody

from rabbit, purified by affinity chromatography

• Sinônimo(s): Caspase-5, CASP-5, ICE(rel)-III, Protease ICH-3, Protease TY, Caspase-5 subunit p202.Caspase-5 subunit p10
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• purificado por: affinity chromatography
• reatividade de espécies: human
• técnica(s): immunocytochemistry: suitable; immunofluorescence: suitable; western blot: suitable
• nº de adesão UniProt: P51878
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... CASP5(838)

Descrição

Descrição geral

Caspase-5 (CASP5) is a member of the peptidase C14A family that can be divided into the apoptotic and inflammatory caspase subfamilies. Members of this subfamily include caspase-1, -4, -5, and -12. When activated, these caspases result in the cleavage and activation of proinflammatory cytokines such as IL-1beta and IL-18. Caspase-5 is expressed in barely detectable amounts in most tissues except brain, with highest levels being found in lung, liver and skeletal muscle. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts.

Especificidade

This antibody recognizes the intermediate domain of Caspase-5.

Imunogênio

Epitope: Intermediate domain

KLH-conjugated linear peptide corresponding to the intermediate domain of human Caspase-5.

Aplicação

Detect Caspase 5 using this rabbit polyclonal antibody, Anti-Caspase-5 Antibody validated for use in western blotting, ICC & Immunofluorescence.

Immunocytochemistry Analysis: 2 µg/mL from a representative lot detected Caspase-5 in P815 cells.

Immunofluorescence Analysis: 2 µg/mL from a representative lot detected Caspase-5 in P815 cells.

Research Category
Signaling

Research Sub Category
Developmental Signaling

Qualidade

Evaluated by Western Blotting in Ramos cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected Caspase-5 in Ramos cell lysate.

Descrição-alvo

~48 kDa observed. Uncharacterized bands may appear in some lysates.

forma física

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Nota de análise

Control
Ramos cell lysate

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable