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Documentos Principais

ABD115

Sigma-Aldrich

Anti-MUSTN1

from rabbit, purified by affinity chromatography

Sinônimo(s):

Musculoskeletal embryonic nuclear protein 1

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

purificado por

affinity chromatography

reatividade de espécies

human, mouse

reatividade da espécie (prevista por homologia)

rat (based on 100% sequence homology)

embalagem

antibody small pack of 25 μg

técnica(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

Isotipo

IgG

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

ambient

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... MUSTN1(389125)

Descrição geral

Musculoskeletal embryonic nuclear protein 1 (UniProt: Q8IVN3; also known a MUSTN1) is encoded by the MUSTN1 gene (Gene ID: 389125) in human. MUSTN1 is a small protein of the MUSTANG family that is found predominantly in the musculoskeletal system. It plays a role in the development and regeneration of the musculoskeletal system. It localizes to the nucleus and specifically, spatially in mesenchymal cells of the developing limbs and in the fracture callus in periosteal osteoprogenitor cells, proliferating chondrocytes, and young active osteoblasts. MUSTN1 sequence is highly homologous in vertebrates and contains a nuclear localization sequence without any other significant motifs. MUSTN1 is highly expressed during embryogenesis and is essential for chondrocyte proliferation and differentiation. (Ref.: Gersch, RP and Hadjiargyrou, M (2009). Bone 45(2); 330-338).

Especificidade

This rabbit polyclonal antibody detects Musculoskeletal embryonic nuclear protein 1 (MUSTN1) in human and mouse. It targets an epitope within 12 amino acids from the C-terminal region.

Imunogênio

Epitope: C-terminus
KLH-conjugated linear peptide corresponding to 12 amino acids from the C-terminal region of human Musculoskeletal embryonic nuclear protein 1.

Aplicação

Anti-MUSTN1, Cat. No. ABD115, is a rabbit polyclonal antibody that detects human and murine Musculoskeletal embryonic nuclear protein 1 and has been tested for use in Immunohistochemistry (Paraffin) and Western Blotting.
Research Category
Cell Structure
Western Blotting Analysis: 2 µg/mL from a representative lot detected MUSTN1 in human heart tissue lysate.
Immunohistochemistry Analysis: A 1:250-1,000 dilution from a representative lot detected MUSTN1 in human skeletal muscle, mouse embryo, and mouse embryonic lung tissues.
Western Blotting Analysis: 2 µg/mL from a representative lot detected MUSTN1 in human heart tissue lysate.

Immunohistochemistry Analysis: A 1:250-1,000 dilution from a representative lot detected MUSTN1 in human skeletal muscle, mouse embryo, and mouse embryonic lung tissues.

Qualidade

Evaluated by Western Blotting in C2C12 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected MUSTN1 in C2C12 cell lysate.

Descrição-alvo

~13 kDa observed; 8.91 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

forma física

Affinity Purified
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine, 0.15 M NaCl, pH7.4 with 0.05% sodium azide.
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine, 0.15 M NaCl, pH7.4 with 0.05% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.
Stable for 1 year at 2-8°C from date of receipt.

Outras notas

Concentration: Please refer to lot specific datasheet.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Classe de risco de água (WGK)

WGK 1


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