AB3841

Anti-Connexin 43 Antibody, phospho-specific (Ser368)

Chemicon^®, from rabbit

• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• clone: polyclonal
• application: WB
• reatividade de espécies: hamster, mouse, rat, monkey, human
• técnica(s): western blot: suitable
• citations: 3

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• purificado por: affinity chromatography
• reatividade de espécies: hamster, mouse, rat, monkey, human
• fabricante/nome comercial: Chemicon^®
• técnica(s): western blot: suitable
• nº de adesão NCBI: NM_000165.3
• nº de adesão UniProt: P17302
• Condições de expedição: dry ice
• modificação pós-traducional do alvo: phosphorylation (pSer368)
• Informações sobre genes: human ... GJA1(2697)

Descrição

Especificidade

Recognizes Ser368 phosphorylated Connexin 43. Connexin 43 (Cx43) is a member of the large family of gap junction proteins. Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels. Clusters of these channels assemble to make gap junctions. Gap-junction communication is important in development and regulation of cell growth.

Imunogênio

Epitope: phospho-specific (Ser368)

KLH-conjugated, synthetic phospho-peptide corresponding to residues surrounding Ser368 of human Connexin 43.

Aplicação

Research Category
Cell Structure

Research Sub Category
Adhesion (CAMs)

This Anti-Connexin 43 Antibody, phospho-specific (Ser368) is validated for use in WB for the detection of Connexin 43.

Western blotting 1:1,000 (for best results, incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight)

Optimal working dilutions must be determined by the end user.

forma física

Protein A and peptide affinity purified immunoglobulin. Liquid in 10 mM sodium HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA, with 50% glycerol.

Armazenamento e estabilidade

Maintain at -20ºC for 12 months after date of receipt. Do not aliquot.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2