AB10514P

Anti-Serotonin Transporter Antibody

1 mg/mL, from rabbit

• Sinônimo(s): solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, sodium-dependent serotonin transporter, serotonin transporter, Solute carrier family 6 member 4, Na+/Cl- dependent serotonin transporter, 5HT transporter, 5-hydroxytryptamine tr
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• purificado por: affinity chromatography
• reatividade da espécie (prevista por homologia): sheep (100% homology), rat (100% homology), bovine (100% homology), monkey (100% homology), human (100% homology), horse (100% homology), mouse (100% homology), chimpanzee (100% homology)
• concentração: 1 mg/mL
• técnica(s): western blot: suitable
• nº de adesão UniProt: P31645
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... HTT(3064)

Descrição

Descrição geral

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Especificidade

Other species have not been tested.

The antibody reacts with the 70 kDa serotonin transporter protein.

Imunogênio

Epitope: Center region

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human serotonin transporter.

Aplicação

Research Category
Neuroscience

Research Sub Category
Ion Channels & Transporters

This Anti-Serotonin Transporter Antibody is validated for use in WB for the detection of Serotonin Transporter.

Qualidade

Western Blot Analysis: 1:1000 dilution of this antibody detected serotonin transporter on human lung lysate.

Descrição-alvo

70 kDa

Ligação

Replaces: AB1594P

forma física

Antigen Affinity Purified

Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.

Armazenamento e estabilidade

Store at 2-8°C for 1 year from date of receipt.

Nota de análise

Control
Western Blot : Human lung lysate.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable