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Merck
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Documentos Principais

411543

Sigma-Aldrich

Mouse Anti-Human IgG₁, Fc Fragment Specific (HP6069) Biotin Conjugate

liquid, clone HP6069, Calbiochem®

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.77

fonte biológica

mouse

Nível de qualidade

forma do anticorpo

purified antibody

tipo de produto de anticorpo

secondary antibodies

clone

HP6069, monoclonal

Formulário

liquid

não contém

preservative

fabricante/nome comercial

Calbiochem®

condição de armazenamento

OK to freeze
avoid repeated freeze/thaw cycles

Isotipo

IgG

Condições de expedição

ambient

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Descrição geral

Purified mouse monoclonal antibody conjugated to biotin. Recognizes human IgG1 Fc fragment.
This Mouse Anti-Human IgG₁, Fc Fragment Specific (HP6069) Biotin Conjugate is validated for use in Enzyme Immunoassay for the detection of Human IgG₁, Fc Fragment Specific.

Aplicação

Enzyme Immunoassay (1:500-1:2000)

Embalagem

Please refer to vial label for lot-specific concentration.

Advertência

Toxicity: Standard Handling (A)

Outras notas

Antibody should be titrated for optimal results in individual systems.



Cross-reactivity by ELISA against human myeloma proteins:

Human IgG1: 100%

Human IgG2: ≤0.1%

Human IgG3: ≤0.2%

Human IgG4: ≤0.1%

Human IgM: ≤0.1%

Human IgA: ≤0.1%

Human IgE: ≤0.1%



Cross-reactivity by ELISA against chimeric antibodies:

Human IgG1: 100%

Human IgG2: <0.02%

Human IgG3: <0.02%

Human IgG4: <0.02%

Human IgM: <0.02%

Human IgA: <0.01%

Human IgE: <0.001%

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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F J Fasullo et al.
Clinical chemistry, 35(3), 364-368 (1989-03-01)
The objective of this study was to develop a clinical laboratory method for subclass typing of human immunoglobulin G (IgG) paraproteins. Serum proteins were isoelectrically focused (IEF) in a mini-gel and passively blotted by capillary diffusion onto untreated nitrocellulose. Unreacted
R G Hamilton
Annales de biologie clinique, 48(7), 473-477 (1990-01-01)
This study demonstrates the utility of a panel of genetically-engineered human-mouse chimeric antibodies with variable region specificity for a hapten, NP, and constant regions analogous to the different human immunoglobulin isotypes as quality control reagents. They performed well as isotype-restricted
R Jefferis et al.
Immunology letters, 10(3-4), 223-252 (1985-01-01)
Seventy-four monoclonal antibodies (McAb) of putative specificity for human IgG (11), the IgG sub-classes (59) or Gm allotypes (4) have been evaluated for reactivity and specificity in eight laboratories employing different assay techniques or protocols. For the IgG, IgG3, IgG4
R G Hamilton
Clinical chemistry, 33(10), 1707-1725 (1987-10-01)
Complement activation, cell surface-receptor binding, blocking activity, and possibly placental transfer are among the biologically important functional differences that have been detected between the four human IgG subclasses by use of polyclonal antisera. In 1985, a IUIS/WHO panel of immunologists

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