344215

Formononetin

A phytoestrogenic isoflavone found in soy-based foods.

• Sinônimo(s): Formononetin, 7-Hydroxy-3-(4ʹ-methoxyphenyl)-4H-benzopyran-4-one
• Fórmula empírica (Notação de Hill): C₁₆H₁₂O₄
• Número CAS: 485-72-3
• Peso molecular: 268.26
• Número MDL: MFCD00016948
• Código UNSPSC: 12352200

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥90% (HPLC)
• forma: solid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; protect from light
• cor: white to off-white
• solubilidade: methanol: 2 mg/mL; DMSO: 200 mg/mL
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C
• InChI: 1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3
• chave InChI: HKQYGTCOTHHOMP-UHFFFAOYSA-N

Descrição

Descrição geral

A non-steroidal phytoestrogenic isoflavone found in soy-based food products. Has been shown to interact with human estrogen receptor with relatively low potency. Induces mammary gland proliferation in mice. Inhibits lecithin peroxidation induced by hydroxyl radicals. Also acts as a selective inhibitor of γ-isoform of alcohol dehydrogenase.

A phytoestrogenic isoflavone found in soy-based foods. Displays potent antioxidant properties and acts as a selective inhibitor of the γ-isoform of alcohol dehydrogenase. Shown to interact with human estrogen receptors with low potency. Induces mammary gland proliferation in mice.

Ações bioquímicas/fisiológicas

Cell permeable: no

Primary Target
Selective inhibitor of the γ-isoform of alcohol dehydrogenase

Product does not compete with ATP.

Reversible: no

Embalagem

Packaged under inert gas

Advertência

Toxicity: Irritant (B)

Reconstituição

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Do not re-freeze any thawed aliquots.

Outras notas

Pool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
Toda, S., and Shirataki, Y. 1999. Phytother. Res.13, 163.
Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res.26, 63.
Keung, W.M. 1995. Biochem. Biophys. Res. Commun.215, 1137.
Wang, W., et al. 1995. Nutr. Cancer23, 131.
Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol.49, 153.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable