239900

Cypermethrin

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC₅₀ = 40 pM). May also have varied effects on ion channels.

• Sinônimo(s): Cypermethrin
• Fórmula empírica (Notação de Hill): C₂₂H₁₉Cl₂NO₃
• Número CAS: 52315-07-8
• Peso molecular: 416.30
• Número MDL: MFCD00055328
• Código UNSPSC: 12352200
• NACRES: NA.77

Propriedades

• descrição: Merck USA index - 14, 2767
• Nível de qualidade: 100
• Ensaio: ≥95% (HPLC)
• Formulário: oil
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze
• solubilidade: DMSO: 15 mg/mL; ethanol: 5 mg/mL
• Condições de expedição: ambient
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: ClC(=CC1C(C1C(=O)OC(c2cc(ccc2)Oc3ccccc3)C#N)(C)C)Cl
• InChI: 1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3
• chave InChI: KAATUXNTWXVJKI-UHFFFAOYSA-N

Descrição

Descrição geral

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC₅₀ = 40 pM). May also have varied effects on ion channels.

Type II pyrethroid insecticide. Potent inhibitor of calcineurin (protein phosphatase 2B, IC₅₀ = 40 pM). May also have varied effects on ion channels.

Ações bioquímicas/fisiológicas

Primary Target
calcineurin

Product does not compete with ATP.

Target IC₅₀: 40 pM against calcineurin (protein phosphatase 2B

Advertência

Toxicity: Toxic (F)

Reconstituição

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Outras notas

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Richter, A., et al. 1995. Biochem. Pharmacol.49, 367.
Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol.43, 1777.
Narahasi, T. 1992. Trends Pharmacol. Sci.13, 236.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS08,GHS07,GHS09
• Palavra indicadora: Warning
• Frases de perigo: H302 + H332,H315,H317,H335,H373,H410
• Declarações de precaução: P273 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P314
• Classificações de perigo: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3
• Órgãos-alvo: Nervous system, Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 212.0 °F - closed cup
• Ponto de fulgor (°C): 100 °C - closed cup