16-220

Anti-phospho-Ser/Thr-Pro MPM-2 Antibody, Cy5 conjugate

Upstate^®, from mouse

• Sinônimo(s): Anti-MPM-2 Cy5 Antibody, Cy5 Anti-MPM-2, Phospho-Ser/Thr-Pro Detection
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• conjugado: CY5 conjugate
• forma do anticorpo: purified antibody
• tipo de produto de anticorpo: primary antibodies
• clone: monoclonal
• reatividade de espécies: vertebrates
• fabricante/nome comercial: Upstate^®
• técnica(s): immunocytochemistry: suitable; immunofluorescence: suitable; western blot: suitable
• Isotipo: IgG1
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: phosphorylation (pSer/pThr)

Descrição

Descrição geral

This antibody recognizes a variety of proteins that are phosphorylated during mitosis.

Progression of cells from interphase to mitosis involves alterations in cell structures and activities. The transition from G2 to M phase is induced by M phase-promoting factor, or MPF. In M phase, many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF. These M-phase phosphoproteins (MPPs, or MPHOSPHs) permit disassembly of interphase structures and generation of M-phase enzymatic activities and structures. Also, known as Forkhead-related protein FKHL16 or Hepatocyte nuclear factor 3 forkhead homolog 11.

Especificidade

Recognizes a phosphorylated epitope (phospho-[Ser/Thr]Pro) found in phosphoproteins such as MAP2, HSP70, cdc25, and DNA topoisomerase IIα, most of which are phosphorylated at the onset of mitosis. The number of phosphoproteins recognized by MPM-2 varies from species to species and with the cell type.

Imunogênio

Mitotic human HeLa cell lysate

Aplicação

Anti-phospho-Ser/Thr-Pro Antibody, MPM-2, Cy5 conjugate is a Mouse Monoclonal Antibody for detection of phospho-Ser/Thr-Pro also known as Mitotic protein #2 & has been tested in IF, WB, ICC.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Cell Cycle, DNA Replication & Repair

Qualidade

Routinely evaluated by immunoblot on colcemid-treated HeLa cell lysates.

forma física

100μg Cy5-conjugated mouse IgG₁ in 200μl of PBS containing 1% BSA, 0.05% Tween^®-20, 0.05% sodium azide.

Protein G Purified

Armazenamento e estabilidade

1 year at 4°C from date of shipment

Nota de análise

Control
Colcemid-treated HeLa cell lysates

Informações legais

TWEEN is a registered trademark of Croda International PLC

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable