14-448-M

Cdk2/Cyclin A Protein, active, 10 µg

Active, C-terminal His6-tagged human full length Cdk2 & N-terminal GST-tagged human full length Cyclin A, for use in Kinase Assays.

• Código UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.41

Propriedades

• fonte biológica: human
• Nível de qualidade: 100
• recombinante: expressed in baculovirus infected Sf21 cells
• linha de produto: Upstate^®
• atividade específica: (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
• peso molecular: M_w 35 kDa
• purificado por: (The cdk2 is purified by Ni2+/NTA agarose and then activated using CAK and repurified by Q Sepharose and Ni2+/NTA agarose. The cyclin A is purified using glutathioneagarose)
• reatividade de espécies: human
• fabricante/nome comercial: Upstate^®
• técnica(s): activity assay: suitable (kinase)
• nº de adesão: (FUNCTION: SwissProt: P24941 # Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2. ); NM_001798.2
• nº de adesão NCBI: NM_001798.2; NM_052827.1
• nº de adesão UniProt: P24941

Descrição

Descrição geral

C-terminal His6-tagged human full length cdk2, and N-terminal GST-tagged human full length cyclin A

Ações bioquímicas/fisiológicas

Protein Target: CDK2/cyclinA

Target Sub-Family: CMGC

Embalagem

Also available in 10 μg size and in bulk

Also available in 250μg size, please inquire for pricing and availability.

Qualidade

routinely evaluated by phosphorylation of Histone H1

Descrição-alvo

CDK2/cyclinA

Ligação

Replaces: 14-407

forma física

The cdk2 is purified by Ni2+/NTA agarose and then activated using CAK and repurified by Q Sepharose^™ and Ni2+/NTA agarose. The cyclin A is purified using glutathioneagarose

Armazenamento e estabilidade

6 months at -70°C

Outras notas

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Informações legais

Sepharose is a trademark of Cytiva

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H317
• Declarações de precaução: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classificações de perigo: Skin Sens. 1
• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°C): Not applicable