112251
α₁-Acid Glycoprotein, Human Plasma
Sinônimo(s):
α₁-Acid Glycoprotein, Human Plasma, α₁-AG, C-AGP, Orosomucoid, α₁M-Seromucoid
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About This Item
Produtos recomendados
fonte biológica
human plasma
Nível de qualidade
Ensaio
≥95% (SDS-PAGE)
forma
lyophilized
fabricante/nome comercial
Calbiochem®
condição de armazenamento
OK to freeze
solubilidade
aqueous buffer: 1 mg/mL
Condições de expedição
ambient
temperatura de armazenamento
2-8°C
Categorias relacionadas
Descrição geral
Native α1-acid glycoprotein from human plasma. Glycoprotein used for the study of the structure of oligosaccharide units. Consists of 40 - 45% carbohydrate. Present in human plasma at concentrations of 55 - 140 mg/100 ml. Clinically,α1-AG is an acute-phase reactant that, together with haptoglobin, indicates acute inflammation. Selectively suppresses the augmentation of NK cell activity by IFN-α and IFN-γ. Theα1-AG:α1-antitrypsin ratio is useful in diagnosis of liver disease. A sialic acid-deficientα1-AG has been observed in serum or urine of patients with Hodgkin’s disease, psoriatic arthritis, diabetes, and chronic myeloid leukemia. Sialic acid-deficientα1-AG has an affinity for vitamin B12.
Native α1-acid glycoprotein from human plasma. Glycoprotein used for the study of the structure of oligosaccharide units. Consists of 40-45% carbohydrate. Present in human plasma at concentrations of 55-140 mg/100 ml. Clinically, α1-AG is an acute phase reactant that, together with haptoglobin, indicates acute inflammation. Selectively suppresses the augmentation of NK cell activity by IFN-α and IFN-γ. The α1-AG:α1-antitrypsin ratio is useful in diagnosis of liver disease. A sialic acid-deficient α1-AG has been observed in serum or urine of patients with Hodgkin′s disease, psoriatic arthritis, diabetes, and chronic myeloid leukemia. Sialic acid-deficient α1-AG has an affinity for vitamin B12.
Advertência
Toxicity: Standard Handling (A)
Nota de preparo
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstituição
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for to 3 months at (-20°C).
Outras notas
Aso, H., et al. 1999. Inflammation 23, 117.
Schmid, K., et al. 1973. Biochemistry 12, 2711.
Schmid, K., et al. 1973. Biochemistry 12, 2711.
Informações legais
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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