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Merck
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07-324

Sigma-Aldrich

Anti-PP2A Antibody, C subunit

Upstate®, from rabbit

Sinônimo(s):

Anti-NEDLBA, Anti-PP2Ac, Anti-PP2CA, Anti-PP2Calpha, Anti-RP-C

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

purificado por

affinity chromatography

reatividade de espécies

bovine, rat, human, mouse

fabricante/nome comercial

Upstate®

técnica(s)

western blot: suitable

Isotipo

IgG

nº de adesão NCBI

NM_002715
NM_004156

nº de adesão UniProt

P67775

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... PPP2CA(5515)

Especificidade

PP2A catalytic subunit

Imunogênio

peptide corresponding to amino acids 290-304 (DPAPRRGEPHVTRRT) of human PP2A

Aplicação

Research Category
Signaling

Neuroscience
Research Sub Category
Oxidative Stress

Neurodegenerative Diseases
This Anti-PP2A Antibody, C subunit is validated for use in WB for the detection of PP2A.

Qualidade

routinely evaluated by immunoblot on RIPA lysates from mouse brain, heart, testes and spleen homogenates

Descrição-alvo

36kDa

forma física

0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, 5mg/ml BSA before the addition of glycerol to 30%
Immunoaffinity Chromatography

Armazenamento e estabilidade

2 years at -20°C

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Characterization of SET/I2PP2A isoforms in dogs.
Yabe, R; Fujiwara, N; Mizuno, T; Usui, T; Ohama, T; Sato, K
The Journal of Veterinary Medical Science null
Satoru Kake et al.
Scientific reports, 7(1), 4279-4279 (2017-06-29)
Canine mammary tumor is the most common neoplasm in female dogs, and it has generated considerable attention as a translational model for human breast cancer. Ser/Thr protein phosphatase 2A (PP2A) plays a critical role as a tumor suppressor, and SET/I2PP2A
Jian Chen et al.
Plant physiology, 166(3), 1519-1534 (2014-10-05)
PROTEIN PHOSPHATASE 2A (PP2A) is a major group of serine/threonine protein phosphatases in eukaryotes. It is composed of three subunits: scaffolding subunit A, regulatory subunit B, and catalytic subunit C. Assembly of the PP2A holoenzyme in Arabidopsis (Arabidopsis thaliana) depends
Nobuyuki Fujiwara et al.
The Journal of biological chemistry, 291(20), 10858-10866 (2016-03-20)
Autophagy is an evolutionarily conserved intracellular degradation system that is involved in cell survival and activated in various diseases, including cancer. Beclin 1 is a central scaffold protein that assembles components for promoting or inhibiting autophagy. Association of Beclin 1
Ha Yin Lee et al.
Science signaling, 11(512) (2018-01-11)
Cancer cells increase glucose metabolism to support aerobic glycolysis. However, only some cancer cells are acutely sensitive to glucose withdrawal, and the underlying mechanism of this selective sensitivity is unclear. We showed that glucose deprivation initiates a cell death pathway
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