05-1946

Anti-USP7 Antibody, clone 1G7

clone 1G7, from mouse

• Sinônimo(s): ubiquitin specific peptidase 7 (herpes virus-associated), Ubiquitin-specific-processing protease 7, ubiquitin specific protease 7 (herpes virus-associated), Herpesvirus-associated ubiquitin-specific protease, Herpes virus-associated ubiquitin-specific pr
• Código UNSPSC: 12352203
• eCl@ss: 32160702

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• tipo de produto de anticorpo: primary antibodies
• clone: 1G7, monoclonal
• reatividade de espécies: human
• reatividade da espécie (prevista por homologia): mouse (based on 100% sequence homology)
• técnica(s): immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• Isotipo: IgG1κ
• nº de adesão NCBI: NP_003461.2
• nº de adesão UniProt: Q93009
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... USP7(7874)

Descrição

Descrição geral

Ubiquitin carboxyl-terminal hydrolase 7 (USP7) is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates.[Saridakis, 2005] Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, Ubiquitin carboxyl-terminal hydrolase 7 activity generally stabilizes its substrate proteins. Ubiquitin carboxyl-terminal hydrolase 7 is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53.[Canning, 2004]

Especificidade

This antibody recognizes USP7.

Imunogênio

Histadine-tagged recombinant protein corresponding to human USP7.

Aplicação

This Anti-USP7 Antibody, clone 1G7 is validated for use in WB, IP, IH for the detection of USP7.

Qualidade

Evaluated by Western Blot in HeLa lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected USP7 on 10 µg of HeLa cell lysate.

Descrição-alvo

~ 128kDa Observed

forma física

Format: Purified

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable