04-1470

Anti-OX40L (CD252) Antibody, clone RM134L

clone RM134L, from rat

• Sinônimo(s): Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, CD252
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: rat
• Nível de qualidade: 100
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: RM134L, monoclonal
• reatividade de espécies: mouse
• técnica(s): flow cytometry: suitable; immunohistochemistry: suitable
• Isotipo: IgG2bκ
• nº de adesão NCBI: NP_033478
• nº de adesão UniProt: P43488
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: mouse ... Tnfsf4(22164)

Descrição

Descrição geral

OX40L (Tumor necrosis factor ligand superfamily member 4; or CD252) is the endogenous ligand of the OX40 receptor. OX40 is localized on activated T-cells and propagates the immune response by promoting division and survival of T-cells, thereby increasing the population of memory CD4 and CD8 T cells produced in response to antigen detection. The OX40/OX40L may also regulate cytokine production and suppress the activity of T-regulatory cells. OX40/OX40L is therefore an important mediator of the immune response. Previous studies have suggested that OX40 signaling maybe involved in the development of autoimmune diseases.

Especificidade

This antibody recognizes the extracellular domain of OX40L.

Imunogênio

Mouse OX40L cDNA-transfected NRK cells

Aplicação

Anti-OX40L (CD252) Antibody, clone RM134L detects level of OX40L (CD252) & has been published & validated for use in Flow Cytometry & IHC.

Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in mouse lung tissue. (Hoshino, A., et al. (2003). Eur. J. Immunol. 33:861–869.)

Qualidade

Evaluated by Flow Cytometry in mouse OX40L/L5178Y cells.

Flow Cytometry Analysis: 10 µg of this antibody detected OX40L in mouse OX40L/L5178Y cells.

Descrição-alvo

22 kDa calculated

forma física

Format: Purified

Nota de análise

Control
Mouse OX40L/L5178Y cells

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable