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Documentos Principais

N-017

Supelco

Normeperidine solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (Notação de Hill):
C14H19NO2
Número CAS:
Peso molecular:
233.31
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

certified reference material

Formulário

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

embalagem

ampule of 1 mL

fabricante/nome comercial

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentração

100 μg/mL in methanol

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicação(ões)

forensics and toxicology

Formato

single component solution

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O=C(OCC)C1(C2=CC=CC=C2)CCNCC1

InChI

1S/C14H19NO2/c1-2-17-13(16)14(8-10-15-11-9-14)12-6-4-3-5-7-12/h3-7,15H,2,8-11H2,1H3

chave InChI

QKHMFBKXTNQCTM-UHFFFAOYSA-N

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Descrição geral

Normeperidine is a toxic primary metabolite of the opioid analgesic meperidine. This Certified Snap-N-Spike® Solution is suitable for use in pain prescription monitoring, clinical toxicology, urine drug testing, or forensic analysis by LC-MS/MS, LC/MS or GC/MS. Meperidine, a synthetic opioid with effects similar to morphine, is used as a painkiller.

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órgãos-alvo

Eyes,Central nervous system

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

49.5 °F - closed cup

Ponto de fulgor (°C)

9.7 °C - closed cup


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Certificados de análise (COA)

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M Shen et al.
Fa yi xue za zhi, 15(4), 204-207 (2003-01-23)
Using meperidine abusers as subjects for this study, we detected in hair meperidine and its metabolites normeperidine, N-OCH3-meperidine and N-AC-meperidine. The content of meperidine and normeperidine of 60 abusers were 103 +/- 130 ng/mg and 117 +/- 143 ng/mg respectively.
X Y Hu et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 29(2), 116-121 (1994-01-01)
Analytical methods of GC/FID and GC/MS for identification and determination of meperidine, an analgesic drug, and its metabolites were established. The determination of meperidine spiked in urine was shown to have a good linear relationship in the range of 0.1-8.0
P A Stone et al.
British journal of anaesthesia, 71(5), 738-740 (1993-11-01)
Patient-controlled analgesia (PCA) with i.v. opioids is prescribed increasingly. We report three cases of norpethidine toxicity in patients receiving pethidine by PCA.
M Shen et al.
Fa yi xue za zhi, 13(1), 3-5 (1997-01-01)
In this study, urine concentrations of meperidine and normeperidine after a single therapeutic dose of meperidine in 5 healthy volunteers have been measured and compared the results to those in meperidine addicts. The results showed that there was a significant
Recognizing normeperidine toxicity.
Patricia McDermot
Nursing, 33(3), 24-24 (2003-03-21)

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