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Supelco

Naltrexone solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (Notação de Hill):
C20H23NO4
Número CAS:
16590-41-3
Peso molecular:
341.40
Número MDL:
MFCD00242996
Código UNSPSC:
41116107
ID de substância PubChem:
329818395
NACRES:
NA.24

grau

certified reference material

Nível de qualidade

300

Formulário

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

embalagem

ampule of 1 mL

fabricante/nome comercial

Cerilliant®

concentração

1.0 mg/mL in methanol

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicação(ões)

forensics and toxicology

Formato

single component solution

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O)CC6CC6

InChI

1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1

chave InChI

DQCKKXVULJGBQN-XFWGSAIBSA-N

Informações sobre genes

human ... OPRD1(4985) , OPRK1(4986) , OPRM1(4988)

Categorias relacionadas

Descrição geral

Naltrexone is an opiate sold under the trade names Revia, Depade and Vivitrol® and is prescribed primarily for the management of alcohol or opiate dependence. This analytical reference standard is applicable for use in LC/MS or GC/MS applications such as pharmaceutical research, forensic analysis, clinical toxicology, pain prescription monitoring or urine drug testing.

Aplicação


  • Naltrexone research solution: Research utilizes naltrexone in thermosensitive gels to enhance microneedle-assisted transdermal delivery, showcasing its potential for non-invasive therapeutic applications and improving drug bioavailability (Polymers (Basel), 2021; doi: 10.3390/polym13060933).

  • Opioid receptor antagonist: A study discusses the historical context of opioid use disorder trials, with naltrexone featured as a pivotal medication in optimizing treatment strategies. This research underscores its importance in addiction studies and the development of effective treatment modalities (Addict Sci Clin Pract, 2021; doi: 10.1186/s13722-021-00223-z).

  • Naltrexone in vitro study: The compound is utilized in a model of ocular neuropathic pain, highlighting its utility in pain management research and its potential role in developing new therapeutic strategies for chronic pain conditions (Transl Vis Sci Technol, 2019; doi: 10.1167/tvst.8.2.6).

  • Naltrexone pharmacological research: Research on Mg²⁺ influx modulation in cardiac myocytes provides insights into ionic exchanges in heart tissues, demonstrating naltrexone′s broader applications in physiological and pharmacological studies (J Physiol Sci, 2019; doi: 10.1007/s12576-018-0625-5).

  • Naltrexone biochemistry application: A study explores mechanical stimulation for reducing ethanol self-administration in rats, indicating naltrexone′s utility in experimental models of addiction and its potential application in behavioral sciences (Evid Based Complement Alternat Med, 2017; doi: 10.1155/2017/6578621).

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Vivitrol is a registered trademark of Alkermes, Inc.

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Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órgãos-alvo

Eyes,Central nervous system

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

49.5 °F - closed cup

Ponto de fulgor (°C)

9.7 °C - closed cup

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Certificados de análise (COA)

Lot/Batch Number

Lamentamos, não temos COA para este produto disponíveis online no momento.

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Przemysław Bieńkowski
Psychiatria polska, 47(1), 117-126 (2013-07-31)
Clinical studies performed over the last decades have indicated that combined therapy, involving pharmaco- and psychotherapy, is an optimal approach to alcohol dependence. Both pharmaco- and psychotherapy should be personalised with a careful balance between patient's needs and his/her clinical
Monthly injectable naltrexone for pathological gambling.
Gihyun Yoon et al.
The American journal of psychiatry, 170(6), 682-683 (2013-06-05)
Jessica H Harvey et al.
Methods in molecular biology (Clifton, N.J.), 995, 43-54 (2013-03-16)
Calcium signaling plays a major role in the function of cells. Measurement of intracellular calcium mobilization is a robust assay that can be performed in a high-throughput manner to study the effect of compounds on potential drug targets. Pharmaceutical companies
Bernard Bihari, MD: low-dose naltrexone for normalizing immune system function.
Bernard Bihari
Alternative therapies in health and medicine, 19(2), 56-65 (2013-04-19)
T V Agibalova et al.
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 113(6 Pt 2), 63-68 (2013-07-28)
This review of literature describes a role of chronic stress in the development of substance dependence including alcohol dependence. It is focused on neurochemical mechanisms of this dependence and approaches to its treatment in people with mental adaptation disorders. An
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