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868584P

Avanti

16:0-d31 SM

Avanti Research™ - A Croda Brand 868584P, powder

Sinônimo(s):

N-palmitoyl-d31-D-erythro-sphingosylphosphorylcholine

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About This Item

Fórmula empírica (Notação de Hill):
C39H48N2O6PD31
Número CAS:
807617-46-5
Peso molecular:
734.22
Número MDL:
MFCD22416907
Código UNSPSC:
12352211
NACRES:
NA.25

Formulário

powder

embalagem

pkg of 1 × 1 mg (868584P-1mg)
pkg of 1 × 5 mg (868584P-5mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 868584P

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COP([O-]

Descrição geral

16:0-d31 SM or N-palmitoyl-d31-D-erythro-sphingosylphosphorylcholine is a deuterium labeled N-palmitoyl-sphingomyelin (SM). N-palmitoyl-SM is a sphingomyelin containing N-linked acyl chain with 16C atoms. Sphingomyelin is found in the outer leaflet of the mammalian cell membrane. It is a vital structural constituent of neurons and lipid bilayers.

Aplicação

16:0-d31 SM or N-palmitoyl-d31-D-erythro-sphingosylphosphorylcholine has been used as an internal standard in mass spectrometry to quantify lipids in biological samples.

Embalagem

5 mL Amber Glass Screw Cap Vial (868584P-1mg)
5 mL Amber Glass Screw Cap Vial (868584P-5mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

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Certificados de análise (COA)

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Structure and lipid interaction of N-palmitoylsphingomyelin in bilayer membranes as revealed by 2H-NMR spectroscopy
Mehnert T, et al.
Biophysical Journal, 90(3), 939-946 (2006)
J Peter Slotte
Biochimica et biophysica acta, 1858(2), 304-310 (2015-12-15)
Sphingomyelin is an important constituent of mammalian cell membranes. Its molecular structure is N-acyl-D-erythro-sphingosylphosphorylcholine. The N-acyls in sphingomyelin often contain 16-24 carbons that are mostly saturated chains; however, the monounsaturated 24:1(Δ15c) acyl chain is also common. In addition to the
Nadine Beckmann et al.
International journal of molecular sciences, 20(24) (2019-12-15)
Farber disease is a rare lysosomal storage disorder resulting from acid ceramidase deficiency and subsequent ceramide accumulation. No treatments for Farber disease are clinically available, and affected patients have a severely shortened lifespan. We have recently reported a novel acid
Kotaro Hama et al.
Journal of lipid research, 61(4), 523-536 (2020-02-23)
X-linked adrenoleukodystrophy (X-ALD) is an inherited disorder caused by deleterious mutations in the ABCD1 gene. The ABCD1 protein transports very long-chain FAs (VLCFAs) from the cytosol into the peroxisome where the VLCFAs are degraded through β-oxidation. ABCD1 dysfunction leads to

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