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Documentos Principais

790427C

Avanti

06:0 PC-d22

Avanti Research - A Croda Brand 790427C

Sinônimo(s):

1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine

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About This Item

Fórmula empírica (Notação de Hill):
C20H18NO8PD22
Número CAS:
Peso molecular:
475.64
Número MDL:
Código UNSPSC:
12352211
NACRES:
NA.12

Ensaio

>99% (TLC)

Formulário

liquid

embalagem

pkg of 1 × 1 mL (790427C-10mg)

fabricante/nome comercial

Avanti Research - A Croda Brand 790427C

concentração

10 mg/mL (790427C-10mg)

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

Descrição geral

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.
Phosphatidylcholine is a zwitterionic glycerophospholipid, containing choline. It consists of a head and two tails. Head group contains choline and phosphate. Head is polar and water soluble. The tail group contains two fatty acyl chains esterified with glycerol. Tail group is non-polar and water-insoluble. Phosphatidylcholine is synthesized in the liver by phosphatidylethanolamine methyltransferase (PEMT) pathway. It is also synthesized by the Kennedy pathway and the Lands cycle.

Aplicação

06:0 PC-d22 (1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine) has been used:
  • as bicelles for lipid in HN-HN nuclear overhauser enhancement (NOE) detection
  • as an internal standard in residual algal suspension for liquid chromatography-mass spectrometry analysis (LC-MS/MS)
  • to produce bicelles to investigate C-peptide and membrane interaction by diffusion nuclear magnetic resonance (NMR) and 2D total correlation spectroscopy (TOCSY)

Ações bioquímicas/fisiológicas

Phosphatidylcholine (PC) is a major component of the membrane bilayer. It is involved in the synthesis of signaling molecules. PC is the precursor for the synthesis of sphingomyelin and phosphatidylserine.

Embalagem

5 mL Clear Glass Sealed Ampule (790427C-10mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órgãos-alvo

Central nervous system

Classe de risco de água (WGK)

WGK 3


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Visite a Biblioteca de Documentos

Membrane lipids:phospholipids
General, Organic, and Biological Chemistry, 581-581 (2006)
Biochemistry of Lipids, Lipoproteins and Membranes (2015)
Metabolic and morphological changes of an oil accumulating trebouxiophycean alga in nitrogen-deficient conditions
Ito T, et al.
Metabolomics, 9(1), 178-187 (2013)
Two different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage
Moessinger C, et al.
BMC Cell Biology, 15(1), 43-43 (2014)
pH-dependent interaction between C-peptide and phospholipid bicelles
Unnerstaale S and Maler L
Journal of biophysics (Hindawi Publishing Corporation : Online), 2012(1), 43-43 (2012)

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