790404P
Avanti
18:1 DGS-NTA(Ni)
Avanti Research™ - A Croda Brand
Sinônimo(s):
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt); DOGS NTA
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About This Item
Fórmula empírica (Notação de Hill):
C53H93N2O15Ni
Número CAS:
Peso molecular:
1057.00
Código UNSPSC:
12352211
NACRES:
NA.25
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descrição
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt)
Ensaio
>99% (TLC)
forma
powder
embalagem
pkg of 1 × 10 mg (790404P-10mg)
pkg of 1 × 25 mg (790404P-25mg)
pkg of 1 × 5 mg (790404P-5mg)
fabricante/nome comercial
Avanti Research™ - A Croda Brand
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
Categorias relacionadas
Descrição geral
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] nitrilotriacetic acid (NTA) (18:1 DGS-NTA(Ni)) is a conjugated phospholipid that contains nickel. NTA chelates with four of the six coordination sites present in nickel ion.
Aplicação
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt) (18:1 DGS-NTA(Ni)) has been used:
- in the preparation of liposomes with porphyrin-phospholipid (PoP) conjugate for protein and peptide binding studies
- in the preparation of nanosize multillamelar vesicles (NMVs) for antigen delivery studies
- as a component of small unilamellar vesicle (SUV) for planar lipid membrane (PM) preparation
Ações bioquímicas/fisiológicas
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] nitrilotriacetic acid (NTA) (18:1 DGS-NTA(Ni)) is useful in structural biology especially to bind recombinant histidine tagged proteins. Though useful, being nanoparticulate it has stability problems in biological samples. So NTA-lipid conjugate is majorly used as liposomes or as a coating to nanoparticle. DGS-NTA (Ni) based nanosize multillamelar vesicles (NMVs) are potent vaccine delivery system.
Embalagem
5 mL Clear Glass Sealed Ampule (790404P-10mg)
5 mL Clear Glass Sealed Ampule (790404P-25mg)
5 mL Clear Glass Sealed Ampule (790404P-5mg)
Informações legais
Avanti Research is a trademark of Avanti Polar Lipids, LLC
geralmente comprado junto com este produto
Código de classe de armazenamento
11 - Combustible Solids
Certificados de análise (COA)
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