300205S

Pegylated Remote Loadable Liposome (5 mL)

Avanti Research^™ - A Croda Brand

• Sinônimo(s): Pegylated Remote Loadable Liposome
• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• Formulário: aqueous solution
• embalagem: pkg of 1 × 5 mL
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C

Descrição

Descrição geral

Liposomes are artificial phospholipid vesicles, used to encapsulate and stabilize the drugs and improve their pharmacological properties. PEGylated liposomes are the liposomes modified on the surface with polyethylene glycol (PEG). This PEGylation prevents adsorption of plasma proteins to the liposome surface. This blocks the recognition and uptake of liposomes by the reticoloendothelial system (RES), thereby extending the circulation time of liposomes. PEGylated liposomes (PEGlip) aids in improving the pharmacodynamic properties of therapeutic proteins. PEGlip improves passive targeting ability on tumoral tissues by a process called enhanced permeation retention effect. It enhances the therapeutic effect of the drug and reduces the toxicity of encapsulated drug. The characteristics of PEGlip depends on the PEG linked to the surface, graft density and the distance between graft sites. PEGlyation with greater PEG chains improves the blood residence time.

Embalagem

10 mL Clear Glass Vial with Stopper and Crimp Cap (300205S-1EA)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2