Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

934623

Sigma-Aldrich

Microneedle spring applicator set

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Código UNSPSC:
44111809
NACRES:
NA.21

Descrição geral

Microneedles are a platform for transdermal drug delivery. The advantages of microneedles include the delivery of large molecules, painless and less invasive administration of the active pharmaceutical ingredient (API), ease of administration, and improved drug delivery including dose, delivery rate and efficacy. Microneedles are also effective for vaccine delivery due to the abundance of immune cells in the dermis.

The microneedle applicator set can be used with the microneedle templates to make and apply reproducible and high quality microneedle patches for a variety of therapeutics.

Aplicação

Transdermal delivery of a variety to therapeutics including:

  • Nucleic acid delivery
  • Vaccine delivery
  • Protein or peptide delivery
  • Small molecule delivery

Características e benefícios

The microneedle applicator set is specifically designed for applying microneedle patches on the skin. It uses a spring to provide consistent impact force. The transparent cone is engineered to fixate and stretch the skin for effective skin penetration by microneedles. Microneedle patches are affixed on the button, which will be loaded onto the applicator using a loader. The loader and its cap have vent holes to allow effective EO or steam sterilization.

propriedades físicas

Each set comes with:
  • 1 standard spring applicator
  • 1 button
  • 1 loader
  • 1 cap
Product specifications:
  • Dimensions: 21.5mm diameter x 43mm length
  • Loadable patch area: Max. diameter 11mm
  • Spring impact force: 1.6N (average)
  • Biocompatible: Yes
  • Autoclavable: Yes

Outras notas

Suggested instructions for use:

  1. Affix a microneedle patch on the surface of the button.
  2. Push the button into the loader with the microneedles facing inward and the keys facing outward.
  3. To load the button onto the bolt of the applicator, hold the loader and align its kits to fit into the holes of the bolt.
  4. Push the loader and bolt to cock the applicator, and turn the loader 90 degrees to lock the button into the bolt.
  5. Remove the loader to expose the microneedle patch. Applicator is ready to use.

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documentos section.

Se precisar de ajuda, entre em contato Atendimento ao cliente

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Jie Xu et al.
Molecules (Basel, Switzerland), 26(19), 5912-5912 (2021-10-14)
A microneedle (MN) is a painless and minimally invasive drug delivery device initially developed in 1976. As microneedle technology evolves, microneedles with different shapes (cone and pyramid) and forms (solid, drug-coated, hollow, dissolvable and hydrogel-based microneedles) have been developed. The

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica