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765457

Sigma-Aldrich

Gold nanoparticles

10 nm diameter, carboxylic acid functionalized, PEG 3000, OD 50, dispersion in H2O

Sinônimo(s):

Gold nanoparticles COOH functionalized, Au NP COOH, Gold Colloid

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About This Item

Código UNSPSC:
12162002
NACRES:
NA.23

Materiais

PEG 3000

Nível de qualidade

100

forma

dispersion in H2O
nanoparticles

embalagem

glass bottle of 1 mL

DO

50

diâmetro

10 nm

pH

6.0-8.0 (25 °C)

solubilidade

water: miscible

densidade

1.00 g/cm3

λmax

520 nm

grupo funcional

carboxylic acid

temperatura de armazenamento

2-8°C

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Descrição geral

Carboxylic acid functionalized GNPs form conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.

Aplicação

Carboxylic acid functionalized, PEG 3000, OD 50, and H2O dispersed gold nanoparticles (10 nm) (AuNPs) can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy. AUNPs may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
The carboxylic acid group binds with various proteins and is used in targeted drug delivery and gene therapy.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
MKCP7677
MKCM4667
MKBZ8814V
MKBN9349V
MKBL5789V

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Visite a Biblioteca de Documentos

Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 6, 1-4 (2020)
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)

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