230995

2-(2-Bromoethyl)-1,3-dioxolane

96%

• Sinônimo(s): 3-Bromopropionaldehyde ethylene acetal
• Fórmula empírica (Notação de Hill): C₅H₉BrO₂
• Número CAS: 18742-02-4
• Peso molecular: 181.03
• Beilstein: 103516
• Número CE: 242-551-1
• Número MDL: MFCD00003216
• Código UNSPSC: 12352100
• ID de substância PubChem: 24853846
• NACRES: NA.22

Propriedades

• Nível de qualidade: 200
• Ensaio: 96%
• forma: liquid
• contém: sodium bicarbonate as stabilizer
• índice de refração: n20/D 1.479 (lit.)
• pb: 68-70 °C/8 mmHg (lit.)
• densidade: 1.542 g/mL at 25 °C (lit.)
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: BrCCC1OCCO1
• InChI: 1S/C5H9BrO2/c6-2-1-5-7-3-4-8-5/h5H,1-4H2
• chave InChI: GGZQLTVZPOGLCC-UHFFFAOYSA-N

Descrição

Descrição geral

Copper-catalyzed borylation of 2-(2-bromoethyl)-1,3-dioxolane with bis(pinacolato)diboron followed by treatment with potassium bifluoride affords the key organotrifluoroborate reagent.

2-(2-Bromoethyl)-1,3-dioxolane is a cyclic ether derivative with a dioxolane ring, used as a building block in organic synthesis and polymer industry.

Aplicação

2-(2-Bromoethyl)-1,3-dioxolane was used:

• as starting reagent for the synthesis of (5Z,9Z)-5,9-hexadecadienoic acid, (5Z,9Z)-5,9-nonadecadienoic acid and (5Z,9Z)-5,9-eicosadienoic acid
• in synthesis of 1-deoxy-castanospermine and 1-deoxy-8a-epi-castanospermine
• in asymmetric total synthesis of both enantiomers of marine mollusk metabolite pulo′upone via Evans′ asymmetric Diels-Alder reaction
• as alkylating agent for amines, dithianes and carboximides
• with eynamides and sodium azide in a "one-pot" synthesis of triazoles

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H301,H315,H319,H335
• Declarações de precaução: P261 - P264 - P271 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 149.0 °F - closed cup
• Ponto de fulgor (°C): 65 °C - closed cup
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter