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Merck

SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

Sinônimos:
CERIII, CIAT, EIEE13, MED, NaCh6, Nav1.6, PN4
Espécies:
ID UniProtKB:
ID do gene:
  • Human(6334) Summary: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20273) sodium channel, voltage-gated, type VIII, alpha
  • Rat(29710) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(426869) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(100857835) sodium channel, voltage gated, type VIII, alpha subunit
  • Horse(100052777) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic cat(101096578) sodium channel, voltage gated, type VIII, alpha subunit
  • dog(477604) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic guinea pig(100734003) sodium channel, voltage gated, type VIII, alpha subunit
  • naked mole-rat(101711868) sodium channel, voltage gated, type VIII, alpha subunit
  • cow(537277) sodium channel, voltage gated, type VIII, alpha subunit
  • sheep(101113744) sodium channel, voltage gated, type VIII, alpha subunit

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Antibodies

Product Number
Descrição
Reatividade de espécies
Aplicação
Anti-SCN8A Sodium Channel Antibody, Chemicon®, from rabbit,
Reatividade de espécies
mouse, rat
Aplicação
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-SCN8A antibody produced in mouse, clone 4G7, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence

western blot
Anti-SCN8A, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
western blot
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence

Small Molecule - Blocker

Product Number
Descrição
Espécies
Lidocaína, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
Lidocaína, solid,
Espécies
human
Procaine hydrochloride, ≥97%,
Espécies
human
Lidocaine, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
Procainamide hydrochloride, ≥98% (HPLC),
Espécies
human

esiRNA

Product Number
Descrição
Espécies
MISSION® esiRNA, targeting mouse Scn8a,
Espécies
mouse